Could a poop pill boost cancer treatment? new trial tests gut bacteria transplant for stubborn colorectal cancer

NCT ID NCT07486492

First seen Apr 25, 2026 · Last updated May 10, 2026 · Updated 3 times

Summary

This early-stage study tests whether transplanting gut bacteria from young donors (fecal microbiota transplant) can make immunotherapy and chemotherapy work better for people with a hard-to-treat type of metastatic colorectal cancer (MSS mCRC). Ten patients aged 18-75 who have already tried first-line treatment will receive six bacteria transplants along with standard drugs. The main goal is to check safety, with a secondary look at whether the combination can shrink tumors or slow cancer growth.

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