Could poop pills help fight breast cancer? new trial aims to find out

NCT ID NCT07292142

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests whether fecal microbiota transplants (FMT) from healthy donors can safely be added to standard chemotherapy and immunotherapy for triple-negative breast cancer. About 125 patients will take part, first in an observation phase and then in a treatment phase. The goal is to see if changing the gut bacteria can help more tumors respond fully to treatment before surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fecal microbiota transplantation (FMT) from healthy donors

What this could lead to

If it works, this could point toward a way to make standard breast cancer treatment more effective for patients whose tumors don't fully respond.

What could go wrong

This is a very early, small pilot study (Phase 1/2) focused on safety and feasibility, not yet on effectiveness. The approach may not improve outcomes and could cause side effects from the transplant.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jewish General Hospital

    Montreal, Quebec, H3T 1E2, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • London Health Sciences Center

    London, Ontario, Canada

    Contact Email: •••••@•••••

  • The Ottawa Hospital Cancer Centre

    Ottawa, Ontario, Canada

    Contact Email: •••••@•••••