New shot could help young boys with hemophilia avoid bleeding episodes

NCT ID NCT07285460

First seen Jan 10, 2026 · Last updated May 15, 2026 · Updated 19 times

Summary

This study tests a medicine called fitusiran in boys aged 1 to under 12 with severe hemophilia A or B, including those whose bodies have developed antibodies that block standard treatments. The goal is to see if regular shots of fitusiran can reduce the number of bleeding episodes. About 85 boys will take part, some switching from their usual care and others joining directly.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cure 4 The Kids Foundation- Site Number : 8400001

    RECRUITING

    Las Vegas, Nevada, 89147, United States

  • Hackensack Meridian Health - Hackensack University Medical Center- Site Number : 8400008

    RECRUITING

    Hackensack, New Jersey, 07601, United States

  • Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo- Site Number : 0760004

    RECRUITING

    São Paulo, 05403-000, Brazil

  • Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto- Site Number : 0760003

    RECRUITING

    Ribeirão Preto, São Paulo, 14051140, Brazil

    Contact Phone: •••-•••-••••

    Contact

  • Investigational Site Number : 0560001

    RECRUITING

    Brussels, 1200, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Investigational Site Number : 0560002

    RECRUITING

    Brussels, 1020, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Investigational Site Number : 1240003

    RECRUITING

    Montreal, Quebec, H3T 1C5, Canada

  • Investigational Site Number : 1580001

    RECRUITING

    Taipei, 100, Taiwan

  • Investigational Site Number : 1580002

    RECRUITING

    Taichung, 402, Taiwan

  • Investigational Site Number : 3560001

    RECRUITING

    Pune, 411004, India

  • Investigational Site Number : 3560002

    RECRUITING

    Mumbai, 400022, India

  • Investigational Site Number : 3800001

    RECRUITING

    Milan, Milano, 20122, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Investigational Site Number : 3800002

    RECRUITING

    Florence, Firenze, 50134, Italy

  • Investigational Site Number : 3800003

    RECRUITING

    Rozzano, Milano, 20089, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Investigational Site Number : 6160002

    RECRUITING

    Wroclaw, Lower Silesian Voivodeship, 50-556, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Investigational Site Number : 6420001

    RECRUITING

    Iași, 700309, Romania

  • Investigational Site Number : 6420003

    RECRUITING

    Timișoara, 300011, Romania

  • Investigational Site Number : 7240001

    RECRUITING

    Esplugues de Llobregat, Barcelona [Barcelona], 08950, Spain

  • Investigational Site Number : 7240002

    RECRUITING

    Madrid, 28046, Spain

  • Investigational Site Number : 7240003

    RECRUITING

    Zaragoza, 50009, Spain

  • Investigational Site Number : 7920001

    RECRUITING

    Istanbul, 34093, Turkey (Türkiye)

    Contact

    Contact Phone: •••-•••-••••

  • Investigational Site Number : 7920002

    RECRUITING

    Izmir, 35100, Turkey (Türkiye)

    Contact Phone: •••-•••-••••

    Contact

  • The Center for Inherited Blood Disorders- Site Number : 8400009

    RECRUITING

    Orange, California, 92868, United States

  • The Luskin Orthopaedic Institute for Children- Site Number : 8400013

    RECRUITING

    Los Angeles, California, 90007, United States

Conditions

Explore the condition pages connected to this study.