New hope for frail myeloma patients: shorter drug combos show promise

NCT ID NCT07107529

First seen Apr 30, 2026 · Last updated May 14, 2026 · Updated 4 times

Summary

This study tests two new drug combinations (teclistamab plus daratumumab or talquetamab plus daratumumab) given for a fixed time in 150 frail patients newly diagnosed with multiple myeloma. The goal is to see how long the cancer stays under control and how well patients tolerate the treatment. Participants must be 18 or older and have measurable disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ES-Barcelona-H.U. Vall d'Hebrón [06-002]

    NOT_YET_RECRUITING

    Barcelona, Spain

  • ES-Las Palmas-H.U. de Gran Canaria Dr Negrín [06-030]

    NOT_YET_RECRUITING

    Las Palmas, Spain

  • ES-Murcia-H.U. Virgen de la Arrixaca [06-016]

    RECRUITING

    Murcia, Spain

  • ES-Salamanca-H.U. de Salamanca [06-021]

    NOT_YET_RECRUITING

    Salamanca, Spain

  • IT-Ascoli Piceno-Ospedale Mazzoni [01-016]

    RECRUITING

    Ascoli Piceno, Italy

  • IT-Bari-A.O.U. Consorziale Policlinico - Medicina Interna [01-018]

    NOT_YET_RECRUITING

    Bari, Italy

  • IT-Bergamo-A.O. Papa Giovanni XXIII [01-003]

    NOT_YET_RECRUITING

    Bergamo, Italy

  • IT-Bologna-A.O.U. di Bologna - Policlinico S. Orsola Malpighi [01-004]

    NOT_YET_RECRUITING

    Bologna, Italy

  • IT-Bolzano-Ospedale di Bolzano - Azienda Sanitaria dell'Alto Adige [01-021]

    NOT_YET_RECRUITING

    Bolzano, Italy

  • IT-Como-Ospedale Classificato Valduce [01-104]

    RECRUITING

    Como, Italy

  • IT-Milano-Fondazione IRCCS Ca' Grande Ospedale Maggiore Policlinico [01-039]

    NOT_YET_RECRUITING

    Milan, Italy

  • IT-Milano-Ospedale S. Carlo Borromeo [01-105]

    RECRUITING

    Milan, Italy

  • IT-Novara-A.O.U. Maggiore della Carità [01-010]

    RECRUITING

    Novara, Italy

  • IT-Pescara-Azienda USL di Pescara P.O. dello Spirito Santo [01-053]

    RECRUITING

    Pescara, Italy

  • IT-Roma-ASL Roma 1 [01-101]

    NOT_YET_RECRUITING

    Roma, Italy

  • IT-Roma-Policlinico Umberto I - Università 'Sapienza' [01-013]

    NOT_YET_RECRUITING

    Roma, Italy

  • IT-Torino-A.O.U. Città della Salute e della Scienza di Torino-SSD Clinical trials [01-001]

    NOT_YET_RECRUITING

    Torino, Italy

  • IT-Varese-Ospedale di Circolo [01-111]

    NOT_YET_RECRUITING

    Varese, Italy

  • NL-Amsterdam-Vrije Universiteit Medical Center (VUMC) [02-007]

    NOT_YET_RECRUITING

    Amsterdam, Netherlands

  • NL-Arnhem-Rijnstate Hospital [02-009]

    NOT_YET_RECRUITING

    Arnhem, Netherlands

  • NL-Den Haag-Haga Ziekenhuis [02-016]

    NOT_YET_RECRUITING

    The Hague, Netherlands

  • NL-Enschede-Medisch Spectrum Twente [02-024]

    NOT_YET_RECRUITING

    Enschede, Netherlands

  • NL-Groningen-University Medical Center Groningen [02-030]

    NOT_YET_RECRUITING

    Groningen, Netherlands

  • NL-Nieuwegein-S. Antonius Hospital [02-038]

    NOT_YET_RECRUITING

    Nieuwegein, Netherlands

  • NL-Schiedam-Franciscus Vlietland Hospital [02-049]

    NOT_YET_RECRUITING

    Schiedam, Netherlands

  • NL-Sittard-Geleen-Zuyderland Medical Center [02-058]

    NOT_YET_RECRUITING

    Sittard, Netherlands

  • NL-Zwolle-Isala Klinieken [02-057]

    NOT_YET_RECRUITING

    Zwolle, Netherlands

  • NO-Oslo-Oslo University Hospital [23-007]

    NOT_YET_RECRUITING

    Oslo, Norway

  • NO-Tønsberg-Vestfold Hospital Trust [23-012]

    NOT_YET_RECRUITING

    Tønsberg, Norway

Conditions

Explore the condition pages connected to this study.