Pioneering fetal surgery aims to fix birth defect before birth

NCT ID NCT05704257

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests a new fetal surgery to repair complex gastroschisis, a birth defect where the baby's intestines stick out of the belly. Ten pregnant women will undergo a fetoscopic procedure to reduce the bowel and close the skin. The goal is to see if this approach is safe and feasible, with the hope of improving outcomes for these babies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
fetoscopic surgery
What this could lead to
If successful, this could offer a way to repair gastroschisis before birth, potentially reducing complications and improving survival for affected infants.
What could go wrong
This is a very early, small trial with only 10 participants, so results may not apply broadly. The surgery carries risks for both mother and fetus, including preterm birth or fetal death.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

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Other studies related to the condition(s) this trial covers.