New drug trial aims to halt silent kidney killer

NCT ID NCT06935357

Recruiting now Disease control Sponsor: Biogen Source: ClinicalTrials.gov ↗

Summary

This study is testing an investigational drug called felzartamab to see if it can protect the kidneys of adults with IgA nephropathy, a disease that causes protein to leak into the urine and can lead to kidney failure. Researchers will compare felzartamab to a placebo (inactive substance) in 454 participants over two years to see if it reduces urine protein and slows the decline in kidney function. The main goal is to see if the drug can help control the disease and prevent long-term kidney damage.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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AHEPA University General Hospital of Thessaloniki
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AP-HP - Hopital Tenon
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Paris, 75020, France

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Créteil, Val-de-Marne, 94000, France

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Paris, 75010, France

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Brescia, Lombardy, 25123, Italy

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Piacenza, Emilia-Romagna, 29121, Italy

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AZ Groeninge
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Kortrijk, West-Vlaanderen, 8500, Belgium

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Affiliated Hospital of Nantong University
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Nantong, Jiangsu, 226001, China
Ajou University Hospital
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Suwon, Gyeonggido, 16499, South Korea
All India Institute of Medical Sciences ( AIIMS ) - Raipur
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Raipur, Chhattisgarh, 492099, India
American Clinical Trials LLC
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Acworth, Georgia, 30101, United States

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Ankara Bilkent Sehir Hastanesi
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Ankara, 34899, Turkey (Türkiye)

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Brookhaven, Mississippi, 39601, United States

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Aotearoa Clinical Trials Trust- Middlemore Hospital
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Auckland, 2025, New Zealand
Applied Research Center of Arkansas
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Little Rock, Arkansas, 72205, United States

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Novara, Piedmont, 28100, Italy

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Trieste, Friuli Venezia Giulia, 34149, Italy

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Beijing, Beijing Municipality, 102218, China
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Boston, Massachusetts, 02115-6110, United States

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CDC Research Institute, LLC
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Port Saint Lucie, Florida, 34952, United States

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Orléans, Loiret, 45067, France

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Bordeaux, Gironde, 33076, France

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Reims, Grand Est, 51092, France

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Strasbourg, Bas-Rhin, 67091, France

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San Miguel de Tucumán, Tucumán Province, T4000CBC, Argentina

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Cangzhou Central Hospital
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Cangzhou, Hebei, 61011, China
Central Florida Kidney Specialists
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Orlando, Florida, 32806, United States

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La Roche-sur-Yon, Vendée, 85925, France

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Braga, 4710-243, Portugal

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Juiz de Fora, Minas Gerais, 36010, Brazil

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Ranica, Lombardy, 24020, Italy

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Chang Gung Memorial Hospital, Linkou
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Taoyuan District, Taiwan, Province of China, 33305, Taiwan
Charité - Universitätsmedizin Berlin
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Berlin, 10117, Germany

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China Medical University Hospital - PPDS
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Taichung, Taiwan, Province of China, 40447, Taiwan
Clinica de la Costa S.A.S. - PPDS
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Barranquilla, Atlántico, 80020, Colombia
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Rijeka, 51000, Croatia

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Cliniques Universitaires Saint-Luc
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Brussels, 1200, Belgium

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Concord Repatriation General Hospital
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New South Wales, New South Wales, 2060, Australia
Consultorios Médicos Dr. Doreski - Fundacion Respirar - PPDS
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Buenos Aires, B1605, Argentina

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DOM Centro de Reumatología
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Buenos Aires, C1111AAH, Argentina

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Daqing Oilfield General Hospital
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Daqing, Heilongjiang, 163001, China
Elixia Health - Michigan Kidney Consultants, LLC - Elixia - PPDS
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Pontiac, Michigan, 48341, United States

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San Juan, 00927, Puerto Rico

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Oxnard, California, 93030, United States

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Far Eastern Memorial Hospital
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New Taipei City, Taiwan, Province of China, 220216, Taiwan
Freire Pesquisa Clínica
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Belo Horizonte, Minas Gerais, 30150-320, Brazil

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Fu Yang People's Hospital - South Campus
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Fuyang, Anhui, 236000, China
Fujita Health University Hospital
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Toyoake-shi, Aiti, 470-1192, Japan
Fukushima Medical University Hospital
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Fukushima, Hukusima, 960-1247, Japan
Fundacio Puigvert
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Viladecans, Barcelona, 8840, Spain

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Fundação Universidade de Caxias do Sul - Instituto de Pesquisas em Saúde
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Caxias do Sul, Rio Grande do Sul, 95070-560, Brazil

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Mulhouse, Haut-Rhin, 68100, France

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Gansu Provincial Hospital
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Lanzhou, Gansu, 730000, China
General Hospital of Athens ''G. Gennimatas''
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Athens, Attica, 115 27, Greece

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General Hospital of Athens ''Hippokratio''
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Athens, Attica, 115 27, Greece

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General Hospital of Heraklion Venizeleio
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Heraklion, Irakleio, 714 09, Greece

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Gold Coast University Hospital
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Southport, Queensland, 4215, Australia
Government Medical College, Kozhikode
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Kozhikode, Kerala, 673008, India
Griffith University
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Southport, Queensland, 4215, Australia
Hallym University Sacred Heart Hospital
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Anyang-si, Gyeonggido, 14068, South Korea
Hamamatsu University Hospital
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Hamamatsu, Sizouka, 431-3192, Japan
Hanyang University Seoul Hospital
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Seoul, Seoul Teugbyeolsi, 4763, South Korea
Healthy Medical Center S.A.S.
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Henry Ford Hospital
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Detroit, Michigan, 48202, United States

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Hirosaki University Hospital
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Hirosaki-shi, Aomori, 036-8563, Japan
Hokkaido University Hospital
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Sapporo, Hokkaido, 060-8648, Japan
Hopital Foch
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Suresnes, Hauts-de-Seine, 92150, France

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Cáceres, 10003, Spain

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Almagro, Ciudad Autónoma de BuenosAires, C1199ABB, Argentina

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Girona, 17007, Spain

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Madrid, 28041, Spain

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Alcorcón, Madrid, 28922, Spain

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Madrid, 28040, Spain

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Hospital Universitario Miguel Servet
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Zaragoza, 50009, Spain

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Barcelona, 8035, Spain

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Seville, 41009, Spain

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Hospital Universitario de Getafe
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Getafe, Madrid, 10400, Spain

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Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
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São Paulo, 05403-000, Brazil

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Porto Alegre, Rio Grande do Sul, 90035-903, Brazil

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Hospital del Mar
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Barcelona, Catalonia, 8003, Spain

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Hospital of the University of Occupational and Environmental Health, Japan
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Kitakyushu-shi, Hukuoka, 807-8556, Japan
Hôpital Erasme - PPDS
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Anderlecht, Brussels Capital, 1070, Belgium

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INECO Neurociencias Oroño
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Rosario, Santa Fe Province, 2000, Argentina

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Genoa, Liguria, 16132, Italy

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IRCCS Istituto Clinico Humanitas
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Rozzano, Lombardy, 20089, Italy

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Ikeda Municipal Hospital
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Ikeda-shi, Ôsaka, 563-8510, Japan
Inje University Haeundae Paik Hospital
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Busan, 48108, South Korea
Institut klinicke a experimentalni mediciny
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Prague, Praha, Hlavní Mesto, 140 21, Czechia

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Irmandade da Santa Casa de Misericórdia de Belo Horizonte - PPDS
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Belo Horizonte, Minas Gerais, 30150221, Brazil

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The Bronx, New York, 10468, United States

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Ieper, West-Vlaanderen, 8900, Belgium

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Jiading Central Hospital
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Shanghai, Shanghai Municipality, 201899, China
Jikei University Hospital
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Minato-ku, Tokyo, 105-8471, Japan
Jinhua Municipal Central Hospital
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Jinhua, Zhejiang, 321000, China
John Hunter Hospital
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New Lambton, New South Wales, 2305, Australia
Juntendo University Hospital
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Bunkyo-Ku, Tokyo, 113-8431, Japan
Juntendo University Urayasu Hospital
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Urayasu-Shi, Chiba, 279-0021, Japan
Kaohsiung Medical University - Chung-Ho Memorial Hospital
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Kaohsiung City, 807, Taiwan
Kawasaki Medical School Hospital
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Kurashiki, Okayama-ken, 701-0192, Japan
Kidney & Hypertension Center - Apple Valley
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Apple Valley, California, 92307, United States

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King George Medical University
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Lucknow, Uttar Pradesh, 226003, India
Kitasato University Hospital
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Sagamihara-shi, Kanagawa, 252-0375, Japan
Klinicki bolnicki centar Sestre Milosrdnice - Vinogradska cesta 29
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Zagreb, City of Zagreb, 10000, Croatia

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Knoxville Kidney Center, PLLC
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Knoxville, Tennessee, 37923-3624, United States

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Laiko General Hospital of Athens
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Athens, Attica, 11527, Greece

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Leicester General Hospital
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Leicester, Leicestershire, LE5 4PW, United Kingdom

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Lifespan at Rhode Island Hospital
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Providence, Rhode Island, 02903, United States

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M.S. Ramaiah Medical College and Hospital
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Bangalore, Karnataka, 560054, India
MCM Krakow - PRATIA - PPDS
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Krakow, Lesser Poland Voivodeship, 30727, Poland

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Mackay Memorial Hospital-Taipei branch
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Taipei, Taiwan, Province of China, 104449, Taiwan
Manipal Hospital Bangalore
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Bangalore, Karnataka, 560017, India
Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi
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Istanbul, 34899, Turkey (Türkiye)

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Max Super Speciality Hospital - Saket
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New Delhi, National Capital Territory of Delhi, 110017, India
McGill University Health Centre (MUHC)
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Montreal, Quebec, H4A3J1, Canada

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Montana, 3400, Bulgaria

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Lovech, 5500, Bulgaria

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Medical Center Medconsult Pleven OOD
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Pleven, 5800, Bulgaria

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Midwest Nephrology Associates,Inc.
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City of Saint Peters, Missouri, 63376, United States
Nara Medical University Hospital
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Kashihara, Nara, 634-8522, Japan
National Cheng Kung University Hospital
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Dawan, Taiwan, Province of China, 70403, Taiwan
National Hospital Organization Chiba Medical Center Chibahigashi National Hospital
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Chiba, Chiba, 260-8712, Japan
National Institute of clinical Research Administration Office
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Garden Grove, California, 92844-2751, United States
Nephrologisches Zentrum Villingen-Schwenningen
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Villingen-Schwenningen, Baden-Wurttemberg, 78052, Germany

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Nil Ratan Sircar Medical College and Hospital
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Kolkata, West Bengal, 700014, India
Nizams Institute of Medical Sciences
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Hyderabad, Andhra Pradesh, 500082, India
Noble Hospital
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Pune, Maharashtra, 411013, India
North America Research Institute-San Dimas
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San Dimas, California, 91773, United States

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Norzel Medical and Diagnostic Clinic Foundation Corp.
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Cebu City, Cebu, 6000, Philippines
Nova Clinical Research, LLC
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Bradenton, Florida, 34209, United States

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Osaka University Hospital
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Suita-shi, Ôsaka, 565-0871, Japan
Osmania General Hospital
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Hyderabad, Andhra Pradesh, 500012, India
Peking University First Hospital - Changqiao Campus
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Beijing, Beijing Municipality, 100034, China
Polyclinic Bonifarm
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Zagreb, City of Zagreb, 10000, Croatia

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Provecta Research Network
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Houston, Texas, 77054, United States

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Pusan National University Hospital
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Busan, Gwangyeogsi, 49241, South Korea
Qilu Hospital of Shandong University
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Jinan, Shandong, 250012, China
R & H Clinical Research
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Katy, Texas, 77974, United States

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Royal Preston Hospital - NWCRN- PPDS
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Preston, Lancashire, PR2 9HT, United Kingdom

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Royal Research, Corp.
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Hollywood, Florida, 33024, United States

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Royal Stoke University Hospital
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Stoke-on-Trent, Staffordshire, ST4 6QG, United Kingdom

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SCM Clinic - Prywatny Szpital Specjalistyczny
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Krakow, Lesser Poland Voivodeship, 31-559, Poland

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SPZOZ Centralny Szpital Kliniczny UM w Lodzi - ul. Pomorska 251
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Lodz, Lódzkie, 92-213, Poland

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Samsung Medical Center
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Seoul, 6351, South Korea
Sanjay Gandhi Postgraduate Institute of Medical Sciences
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Lucknow, Uttar Pradesh, 226014, India
Scripps Green Hospital
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Carlsbad, California, 92009, United States

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Seoul National University Bundang Hospital
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Seongnam-si, Gyeonggido, 13620, South Korea
Seoul National University Hospital
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Seoul, 03080, South Korea
Seth G S Medical College and K E M Hospital
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Mumbai, Maharashtra, 400012, India
Severance Hospital Yonsei University Health System
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Seoul, Seoul Teugbyeolsi, 3722, South Korea
Shanghai General Hospital - North Campus
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Shanghai, Shanghai Municipality, 200080, China
Shenzhen Hospital of Southern Medical University
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Shenzhen, Guangdong, 510086, China
Showa Medical University Hospital
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Shinagawa-ku, Tokyo, 142-86666, Japan
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
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Chengdu, Sichuan, 610072, China
Sir Ganga Ram Hospital
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New Delhi, National Capital Territory of Delhi, 110060, India
Special Hospital Medico
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Rijeka, 51000, Croatia

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Taipei Medical University Shuang Ho Hospital
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New Taipei City, 235041, Taiwan
Taipei Municipal Wanfang Hospital
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Taipei, Taiwan, Province of China, 116081, Taiwan
Taizhou Hospital of Zhejiang Province - Main
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Taizhou, Zhejiang, 317000, China
Texas Kidney Institute - Dallas
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Dallas, Texas, 95231, United States

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The Affiliated Hospital of Guizhou Medical University
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Guiyang, Guizhou, 550000, China
The First Affiliated Hospital of Anhui Medical University - Jixilu Campus
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Hefei, Anhui, 230022, China
The First Affiliated Hospital of Guangzhou Medical University - Yanjiang Campus
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Guangzhou, Guangdong, 510120, China
The First Affiliated Hospital of Henan Science and Technology University - Jinghua Campus
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Luoyang, Henan, 471003, China
The Jikei University West Medical Center
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Ashikaga-Shi, Tokyo, 326-0843, Japan
The People's Hospital of Guangxi Zhuang Autonomous Region
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Nanning, Guangxi, 530021, China
The Second Affiliated Hospital of Nanjing Medical University
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Nanjing, Jiangsu, 210011, China
The Second Hospital of Hebei Medical University - Main
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Shijiazhuang, Hebei, 50000, China
The Third Hospital of Hebei Medical University
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Shijiazhuang, Hebei, 50000, China
The Vasculitis and Glomerulonephritis Center at Massachusetts General Hospital
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Boston, Massachusetts, 02114-4724, United States

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Tohoku Medical and Pharmaceutical University Hospital
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Sendai, Miyagi, 983-8512, Japan
Tokushima University Hospital
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Tokushima, Tokushima, 770-8503, Japan
Toranomon Hospital Kajigaya
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Kawasaki-shi, Kanagawa, 213-0015, Japan
Townsville Hospital
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Douglas, Queensland, 4814, Australia
Trivandrum Medical College Hospital
NOT_YET_RECRUITING

Trivandrum, Kerala, 695011, India
Twoja Przychodnia - Szczecinskie Centrum Medyczne
RECRUITING

Szczecin, West Pomeranian Voivodeship, 71-434, Poland

Contact Phone: •••-•••-••••

Contact
ULS da Arrábida, EPE - Hospital de São Bernardo
RECRUITING

Setúbal, 2910-446, Portugal

Contact Phone: •••-•••-••••

Contact
ULS da Região de Aveiro, EPE - Hospital Infante D. Pedro
RECRUITING

Aveiro, 3814, Portugal

Contact Phone: •••-•••-••••

Contact
ULS da Região de Leiria, EPE - Hospital de Santo André
RECRUITING

Leiria, 2410-197, Portugal

Contact Phone: •••-•••-••••

Contact
ULS de Coimbra, EPE - Hospitais da Universidade de Coimbra
RECRUITING

Coimbra, 3004-561, Portugal

Contact Phone: •••-•••-••••

Contact
ULS de Gaia/Espinho, EPE - Unidade I
RECRUITING

Vila Nova de Gaia, Lisbon District, 4434-502, Portugal

Contact Phone: •••-•••-••••

Contact
ULS de Lisboa Ocidental, EPE - Hospital Santa Cruz
RECRUITING

Carnaxide, Lisbon District, 2790, Portugal

Contact Phone: •••-•••-••••

Contact
UZ Leuven - PPDS
RECRUITING

Leuven, Vlaams Brabant, 3000, Belgium

Contact Phone: •••-•••-••••

Contact
University Hospital, Kyoto Prefectural University of Medicine
RECRUITING

Kyoto, Kyôto, 602-8566, Japan
University Malaya Medical Centre
RECRUITING

Lembah Pantai, WilayahPersekutuan KualaLumpur, 59100, Malaysia
University Multiprofile Hospital for Active Treatment Sv Ivan Rilski EAD-15 Acad. Ivan Geshov Blvd
RECRUITING

Sofia, 1606, Bulgaria

Contact Phone: •••-•••-••••

Contact
Universitätsklinikum Carl Gustav Carus an der TU Dresden
NOT_YET_RECRUITING

Dresden, Saxony, 1307, Germany

Contact Phone: •••-•••-••••

Contact
Universitätsklinikum Frankfurt, Apotheke Haus 19
RECRUITING

Frankfurt am Main, Hesse, 60596, Germany

Contact Phone: •••-•••-••••

Contact
Universitätsmedizin der Johannes Gutenberg-Universität Mainz
NOT_YET_RECRUITING

Mainz, Rhineland-Palatinate, 55131, Germany

Contact Phone: •••-•••-••••

Contact
Uniwersytecki Szpital Kliniczny Nr 2 PUM w Szczecinie
RECRUITING

Szczecin, 70-110, Poland

Contact Phone: •••-•••-••••

Contact
Uniwersyteckie Centrum Kliniczne w Gdansku - Debinki 7
RECRUITING

Gdansk, Pomeranian Voivodeship, 80-952, Poland

Contact Phone: •••-•••-••••

Contact
Westmead Hospital
RECRUITING

Westmead, New South Wales, 2145, Australia
Wuxi Peoples Hospital
RECRUITING

Wuxi, Jiangsu, 214023, China
Yantai Yuhuangding Hospital
NOT_YET_RECRUITING

Yantai, Shandong, 264000, China
Yichang Central People's Hospital - Wujiagang Campus
RECRUITING

Yichang, Hubei, 443003, China
Yokohama City University Hospital
RECRUITING

Yokohama, Kanagawa, 236-0004, Japan
ZOL Genk - campus Sint-Jan
NOT_YET_RECRUITING

Genk, Limburg, 3600, Belgium

Contact Phone: •••-•••-••••

Contact
Zhongshan Hospital Xiamen University
RECRUITING

Xiamen, Fujian, 361004, China
Zhongshan Hospital of Traditional Chinese Medicine
RECRUITING

Zhongshan, Guangdong, 528401, China
Zydus Hospital
RECRUITING

Ahmedabad, Gujarat, 380081, India

Conditions

Explore the condition pages connected to this study.

IMMUNOGLOBULIN A NEPHROPATHY (IGAN)