New drug could save transplanted kidneys from immune attack
NCT ID NCT06685757
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 35 times
Summary
This study tests a drug called felzartamab in 120 kidney transplant patients whose bodies are attacking their new kidney (antibody-mediated rejection). The drug targets immune cells that make harmful antibodies, aiming to stop damage and keep the kidney working. Participants will receive either felzartamab or a placebo for 24 weeks, then all will get felzartamab for another 28 weeks. The goal is to see if the drug can reduce inflammation and improve kidney health.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ANTIBODY-MEDIATED REJECTION are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Auckland City Hospital
RECRUITINGGrafton, Auckland, 1023, New Zealand
-
CHU Grenoble Alpes Hôpital Michallon
RECRUITINGLa Tronche, 38700, France
Contact Phone: •••-•••-••••
Contact
-
CHU Lyon Hôpital Edouard Herriot
RECRUITINGBordeaux, 32000, France
Contact Phone: •••-•••-••••
Contact
-
California Pacific Medical Center
RECRUITINGSan Francisco, California, 94109, United States
Contact Phone: •••-•••-••••
Contact
-
Cedars-Sinai Medical Center
RECRUITINGLos Angeles, California, 90048, United States
Contact Phone: •••-•••-••••
Contact
-
Centre Hospitalier Universitaire (CHU) de Toulouse - Hôpital de Rangueil
RECRUITINGToulouse, 31400, France
Contact Phone: •••-•••-••••
Contact
-
Charite University
RECRUITINGBerlin, 10117, Germany
Contact Phone: •••-•••-••••
Contact
-
Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-••••
Contact
-
Clinica Privada Velez Sarsfield
RECRUITINGCórdoba, X5000, Argentina
Contact Phone: •••-•••-••••
Contact
-
Cooperman Barnabas Medical Center
RECRUITINGWest Orange, New Jersey, 07039, United States
Contact Phone: •••-•••-••••
Contact
-
Duke University
RECRUITINGDurham, North Carolina, 27705, United States
Contact Phone: •••-•••-••••
Contact
-
Fiona Stanley Hospital
RECRUITINGMurdoch, Western Australia, 6150, Australia
-
Fundação Oswaldo Ramos - Hospital do Rim (HRIM)
RECRUITINGVila Clementino, São Paulo, 04038-002, Brazil
Contact Phone: •••-•••-••••
Contact
-
Hospices Civils de Lyon - Hôpital Édouard Herriot
RECRUITINGLyon, 69003, France
Contact Phone: •••-•••-••••
Contact
-
Hospital Clinic de Barcelona
RECRUITINGCalle Villarroel, Barcelona, 8036, Spain
Contact Phone: •••-•••-••••
Contact
-
Hospital Universitario Miguel Servet
RECRUITINGZaragoza, 50009, Spain
Contact Phone: •••-•••-••••
Contact
-
Hospital Universitario Vall d'Hebron
RECRUITINGHorta-Guinardó, Barcelona, 8035, Spain
Contact Phone: •••-•••-••••
Contact
-
Hospital Universitario de Bellvitge
RECRUITINGL'Hospitalet de Llobregat, Barcelona, 8907, Spain
Contact Phone: •••-•••-••••
Contact
-
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
RECRUITINGCerqueira César, São Paulo, 05403-010, Brazil
Contact Phone: •••-•••-••••
Contact
-
Hospital de Base da Faculdade de Medicina de São José do Rio Preto
RECRUITINGVila São José, São José Do Rio Preto, 15090-000, Brazil
Contact Phone: •••-•••-••••
Contact
-
Hospital del Mar
RECRUITINGCiutat Vella, Barcelona, 8003, Spain
Contact Phone: •••-•••-••••
Contact
-
Houston Methodist
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-••••
Contact
-
Institute for Clinical and Experimental Medicine (IKEM)
RECRUITINGCzechia, Praha 4, 14021, Czechia
Contact Phone: •••-•••-••••
Contact
-
Instituto de Trasplante y Alta Complejidad (ITAC)
RECRUITINGCdad, Autónoma de Buenos Aires, C1425 C1425EGH, Argentina
Contact Phone: •••-•••-••••
Contact
-
Loma Linda
RECRUITINGSan Bernardino, California, 92408, United States
Contact Phone: •••-•••-••••
Contact
-
Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-••••
Contact
-
McGill University
RECRUITINGMontreal, Quebec, H3G 1A4, Canada
Contact Phone: •••-•••-••••
Contact
-
Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
Contact Phone: •••-•••-••••
Contact
-
Medical University of Vienna
RECRUITINGSpitalgasse, State of Vienna, 1090, Austria
Contact Phone: •••-•••-••••
Contact
-
Penn Medicine - Hospital of the University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-••••
Contact
-
Princess Alexandra Hospital
RECRUITINGWoolloongabba, QLD 4102, Australia
-
Providence Healthcare
RECRUITINGOrange, California, 92868, United States
Contact Phone: •••-•••-••••
Contact
-
Royal Melbourne Hospital
RECRUITINGParkville VIC, Australia, 3050, Australia
-
Santa Casa de Misericordia de Porto Alegre - Hospital Dom Vicente Scherer
RECRUITINGCentro Histórico, Porto Alegre - RS, 90020-090, Brazil
Contact Phone: •••-•••-••••
Contact
-
The Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
Contact Phone: •••-•••-••••
Contact
-
The University of British Columbia (UBC)/St. Paul's Hospital part of Providence Health Care
RECRUITINGVancouver, British Columbia, V6T 1Z3, Canada
Contact Phone: •••-•••-••••
Contact
-
Tulane University Health Sciences Center
RECRUITINGNew Orleans, Louisiana, 70112, United States
Contact Phone: •••-•••-••••
Contact
-
UCLA
RECRUITINGLos Angeles, California, 90095, United States
Contact Phone: •••-•••-••••
Contact
-
UT Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
Contact Phone: •••-•••-••••
Contact
-
Universitaetsklinikum Carl Gustav Carus Dresden
RECRUITINGDresden, 1307, Germany
Contact Phone: •••-•••-••••
Contact
-
Universitatsklinikum Hamburg-Eppendorf
RECRUITINGHamburg, 20246, Germany
Contact Phone: •••-•••-••••
Contact
-
University Hospital Basel
RECRUITINGPetersgraben, Basel, 4031, Switzerland
Contact Phone: •••-•••-••••
Contact
-
University of Alberta
RECRUITINGEdmonton, Alberta, T6G 2C8, Canada
Contact Phone: •••-•••-••••
Contact
-
University of California, San Francisco
RECRUITINGSan Francisco, California, 94143, United States
Contact Phone: •••-•••-••••
Contact
-
University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
Contact Phone: •••-•••-••••
Contact
-
University of Cincinnati
RECRUITINGCincinnati, Ohio, 45219, United States
Contact Phone: •••-•••-••••
Contact
-
University of Colorado
RECRUITINGAurora, Colorado, 80045, United States
Contact Phone: •••-•••-••••
Contact
-
University of Kansas
RECRUITINGKansas City, Kansas, 66160, United States
Contact Phone: •••-•••-••••
Contact
-
University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact Phone: •••-•••-••••
Contact
-
University of Nebraska
RECRUITINGOmaha, Nebraska, 68198-5331, United States
Contact Phone: •••-•••-••••
Contact
-
University of Southern California
RECRUITINGLos Angeles, California, 90033, United States
Contact Phone: •••-•••-••••
Contact
-
University of Washington Medical Center
RECRUITINGSeattle, Washington, 98195, United States
Contact Phone: •••-•••-••••
Contact
-
Universitätsklinikum Regensburg
RECRUITINGRegensburg, 93053, Germany
Contact Phone: •••-•••-••••
Contact
-
Universitätsspital Zürich
RECRUITINGZurich, 8091, Switzerland
Contact Phone: •••-•••-••••
Contact
-
Vancouver General Hospital
RECRUITINGVancouver, British Columbia, V5Z 1M9, Canada
Contact Phone: •••-•••-••••
Contact
-
Vanderbilt University
RECRUITINGNashville, Tennessee, 37232, United States
Contact Phone: •••-•••-••••
Contact
-
Virginia Commonwealth University
RECRUITINGRichmond, Virginia, 23298, United States
Contact Phone: •••-•••-••••
Contact
-
Washington University
RECRUITINGSt Louis, Missouri, 63130, United States
Contact Phone: •••-•••-••••
Contact
-
Westmead Hospital
RECRUITINGSydney, New South Wales, 2145, Australia
Conditions
Explore the condition pages connected to this study.