New drug trial aims to halt kidney damage in autoimmune disease
NCT ID NCT06962800
Summary
This study is testing an investigational drug called felzartamab for people with primary membranous nephropathy (PMN), an autoimmune disease that damages the kidneys' filters. The main goal is to see if felzartamab works better than the standard drug tacrolimus at reducing harmful protein in the urine and protecting kidney function over two years. Researchers will enroll 180 adults with PMN to compare the safety and effectiveness of the two treatments.
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Academic Medical Research Institute
RECRUITINGLos Angeles, California, 90022, United States
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Ajou University Hospital
RECRUITINGSuwon, Gyeonggido, 16499, South Korea
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Apogee Clinical Research, LLC
RECRUITINGHuntsville, Alabama, 35805-4104, United States
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Beijing Tsinghua Changgung Hospital
RECRUITINGBeijing, Beijing Municipality, 102218, China
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CINME S.A. - Centro de Investigaciones Metabólicas
RECRUITINGBuenos Aires, C1056ABI, Argentina
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Centro Medico Dra. Laura Maffei- Investigacion Clinica Aplicada
RECRUITINGBuenos Aires, C1425, Argentina
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Centro de Pesquisa Clínica de Nefrologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
RECRUITINGSão Paulo, 05304-000, Brazil
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Chang Gung Memorial Hospital
RECRUITINGTaoyuan District, 33305, Taiwan
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China Medical University Hospital
RECRUITINGTaichung, 40447, Taiwan
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Chung-Ang University Hospital
RECRUITINGSeoul, 6973, South Korea
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Clínica Privada Vélez Sarsfield
RECRUITINGCórdoba, X5016KET, Argentina
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Concord Hospital
RECRUITINGConcord, New South Wales, 2138, Australia
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Daqing Oilfield General Hospital
RECRUITINGDaqing, Heilongjiang, 163001, China
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ECU Physicians Nephrology and Hypertension
RECRUITINGGreenville, North Carolina, 27834, United States
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Elixia Health - Michigan Kidney Consultants, LLC - Elixia - PPDS
COMPLETEDPontiac, Michigan, 48341, United States
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Fu Yang People's Hospital - South Campus
RECRUITINGFuyang, Anhui, 236006, China
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Fundacao Faculdade Regional de Medicina de Sao Jose Do Rio Preto Hospital de Base - PPDS
RECRUITINGSão José do Rio Preto, São Paulo, 15090-000, Brazil
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Gansu Provincial Hospital
RECRUITINGLanzhou, Gansu, 730000, China
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Gold Coast University Hospital
RECRUITINGSouthport, Queensland, 4215, Australia
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Griffith University Clinical Trial Unit
RECRUITINGSouthport, Queensland, 4215, Australia
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Hanyang University Seoul Hospital
RECRUITINGSeoul, 4763, South Korea
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Henry Ford Hospital- A-Basement Research Pharmacy
RECRUITINGDetroit, Michigan, 48202-2608, United States
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Hokkaido University Hospital
RECRUITINGSapporo, Hokkaidô, 060-8648, Japan
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Hospital Canselor Tuanku Muhriz UKM
RECRUITINGCheras, WilayahPersekutuan KualaLumpur, 56000, Malaysia
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Hospital Italiano de Buenos Aires
RECRUITINGBuenos Aires, C1199ABB, Argentina
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Hospital Raja Permaisuri Bainun
RECRUITINGPerak, Pahang, 30450, Malaysia
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Hospital Sao Lucas Da Pontificia Universidade Catolica Do Rio Grande Do Sul (PUCRS)
RECRUITINGPorto Alegre, Rio Grande do Sul, 90610-001, Brazil
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Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo
RECRUITINGRibeirão Preto, São Paulo, 14051-140, Brazil
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Hospital de Clinicas de Porto Alegre
RECRUITINGPorto Alegre, Rio Grande do Sul, 90560-030, Brazil
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Hualien Tzu Chi Hospital
RECRUITINGHualien City, Hualien, 970, Taiwan
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Inje University Haeundae Paik Hospital
RECRUITINGBusan, 48108, South Korea
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James J Peters Veterans Administration Medical Center - NAVREF - PPDS
RECRUITINGThe Bronx, New York, 10468, United States
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Japanese Red Cross Musashino Hospital
RECRUITINGMusashino-shi, Tokyo, 180-8610, Japan
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Juntendo University Urayasu Hospital
RECRUITINGUrayasu-Shi, Chiba, 279-0021, Japan
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Kagawa University Hospital
RECRUITINGKita-Gun Uchiko-Cho, Kagawa-ken, 761-0793, Japan
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Kaohsiung Medical University Chung-Ho Memorial Hospital
RECRUITINGKaohsiung City, 80756, Taiwan
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Knoxville Kidney Center, PLLC
RECRUITINGKnoxville, Tennessee, 37923-3624, United States
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Lanzhou University Second Hospital
RECRUITINGLanzhou, Gansu, 730030, China
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M.S. Ramaiah Medical College and Hospital
RECRUITINGBangalore, Karnataka, 560054, India
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MacKay Memorial Hospital
RECRUITINGTaipei, 104, Taiwan
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Monash Health
RECRUITINGClayton, Victoria, 3168, Australia
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National Cheng Kung University Hospital
RECRUITINGTainan, 70403, Taiwan
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National Hospital Organization Chiba Medical Center Chibahigashi National Hospital
RECRUITINGChia-shi, Chiba, 260-8712, Japan
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Nephrotex Research Group
RECRUITINGDallas, Texas, 75231-0929, United States
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Niigata University Medical & Dental Hospital
RECRUITINGNiigata, Niigata, 951-8520, Japan
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Nizams Institute of Medical Sciences
RECRUITINGHyderabad, Andhra Pradesh, 500082, India
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Noble Hospital
RECRUITINGPune, Maharashtra, 411013, India
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Organización Médica de Investigación
RECRUITINGBuenos Aires, C1015ABO, Argentina
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Osmania General Hospital
RECRUITINGHyderabad, Andhra Pradesh, 500012, India
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Peking University First Hospital - Changqiao Campus
RECRUITINGXichengqu Beijing, Beijing Municipality, 100034, China
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Qilu Hospital of Shandong University
RECRUITINGJinan, Shandong, 250012, China
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Seoul National University Hospital
RECRUITINGSeoul, Seoul Teugbyeolsi, 3080, South Korea
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Social Medical Corporation Yuuaikai Yuuai Medical Center
RECRUITINGTomigusuku-Shi, Okinawa, 901-0224, Japan
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St George Hospital
RECRUITINGKogarah, New South Wales, 2217, Australia
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Taichung Veterans General Hospital
RECRUITINGTaichung, 40705, Taiwan
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Taipei Medical University Hospital - PPDS
RECRUITINGTaipei, 11031, Taiwan
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Taipei Municipal Wanfang Hospital
RECRUITINGTaipei, 116, Taiwan
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The Affiliated Hospital of Guizhou Medical University
RECRUITINGGuiyang, Guizhou, 550004, China
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The Affiliated Hospital of Qingdao University - Xihaian Campus
RECRUITINGQingdao, Shandong, 266555, China
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The First Affiliated Hospital of Henan Science and Technology University - Jinghua Campus
RECRUITINGLuoyang, Henan, 471003, China
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The First Affiliated Hospital of Xian Jiaotong University
RECRUITINGXi'an, Shaanxi, 710061, China
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The First Hospital of Hebei Medical University
RECRUITINGShijiazhuang, Hebei, 50031, China
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The Kitasato Institute Kitasato University Hospital
RECRUITINGSagamihara-Shi Minami-Ku, Kanagawa, 252-0375, Japan
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The Nephrology Group, Inc. - Fresno
RECRUITINGFresno, California, 93720-2989, United States
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The People's Hospital of Guangxi Zhuang Autonomous Region
RECRUITINGNanning, Guangxi, 530021, China
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The Second Affiliated Hospital, Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310009, China
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The Second Hospital of Hebei Medical University - Main
RECRUITINGShijiazhuang, Hebei, 50000, China
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The Second Xiangya Hospital of Central South University
RECRUITINGChangsha, Hunan, 410011, China
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Townsville Hospital
RECRUITINGDouglas, Queensland, 4814, Australia
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UCSF Medical Center
RECRUITINGSan Francisco, California, 94143-2205, United States
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University of Miyazaki Hospital
RECRUITINGMiyazaki, Miyazaki, 889-1692, Japan
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University of Texas Medical Branch
RECRUITINGLeague City, Texas, 77573, United States
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Westmead Hospital
RECRUITINGWestmead, New South Wales, 2145, Australia
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Yantai Yuhuangding Hospital
RECRUITINGYantai, Shandong, 264000, China
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Yokohama City University Hospital
RECRUITINGYokohama, Kanagawa, 236-0004, Japan
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Yueyang People Hospital
RECRUITINGYueyang, Hunan, 414000, China
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Zhongshan Hospital Xiamen University
RECRUITINGXiamen, Fujian, 361004, China
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Zhujiang Hospital of Southern Medical University
RECRUITINGGuangzhou, Guangdong, 510280, China
Conditions
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