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Could poop pills heal gut damage in rare immune disease?

NCT ID NCT05333471

Recruiting now Disease control Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether transplanting healthy donor stool into the gut can reduce colon inflammation in people with chronic granulomatous disease (CGD) who have colitis not helped by standard treatments. Twenty participants aged 10-60 will receive the transplant during a colonoscopy and be followed for 6 months. The goal is to see if this approach safely lowers inflammation and improves gut health.

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Conditions

The condition(s) this trial relates to.

chronic granulomatous disease inborn error of immunity Inflammation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC GRANULOMATOUS DISEASE-ASSOCIATED COLITIS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••