Could your own fat heal Crohn's fistulas and prevent a colostomy bag?

NCT ID NCT05594862

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether injecting a person's own processed fat tissue can heal complex anal fistulas caused by Crohn's disease that have not responded to standard treatments. About 80 adults with Crohn's and active fistulas will receive either the fat injection plus standard care or standard care alone. The main goal is to see if the fistulas close completely by 24 weeks, which could improve quality of life and reduce the need for a permanent colostomy.

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Conditions

The condition(s) this trial relates to.

Crohn disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • IRCCS S Orsola Malpighi

    Bologna, Bologna, Italy