Freeze or melt? study pits two Fat-Reduction devices Head-to-Head

NCT ID NCT01976247

First seen Jul 01, 2026 · Last updated Jul 01, 2026

Summary

This pilot study compares two noninvasive devices—one that freezes fat (cryolipolysis) and one that uses ultrasound energy—to see which works better for reducing belly fat and improving body shape. About 15 healthy women aged 30 to 65 with a normal or slightly overweight body mass index will receive both treatments on opposite sides of their abdomen. A blinded dermatologist will rate cosmetic improvement at 12 weeks to determine which device provides better results.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Noninvasive cryolipolysis device (Zeltiq) and high-intensity focused ultrasound device (Liposonix)

What this could lead to

If one device proves more effective, it could offer a better non-surgical option for fat reduction.

What could go wrong

This is a small, early-phase pilot study with only 15 participants, so results may not apply to everyone. Both devices may cause temporary side effects like bruising or discomfort.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Northwestern University Department of Dermatology

    Chicago, Illinois, 60611, United States