Could a 24-Hour liquid diet make GLP-1 users safer for surgery?

NCT ID NCT06839248

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether a 24-hour clear liquid diet reduces leftover stomach contents in people taking weekly GLP-1 medications (like Ozempic). These drugs can slow digestion, raising the risk of stomach contents entering the lungs during procedures. Researchers will compare the liquid diet to standard fasting rules in 154 adults using a stomach ultrasound to check results.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
24-hour clear liquid diet
What this could lead to
If successful, this could lead to better fasting guidelines for patients on GLP-1 medications, reducing the risk of stomach contents entering the lungs during surgery.
What could go wrong
This is a small, early-stage trial (154 participants) testing a dietary change, not a new drug. Results may not apply to all patients or settings, and the intervention may be hard to follow.

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Conditions

The condition(s) this trial relates to.

aspiration pneumonia Respiratory Aspiration of Gastric Contents

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Melbourne Gastro Oesophageal Surgery (MGOS)

    RECRUITING

    Melbourne, Victoria, 3002, Australia

  • St Vincent's Hospital Melbourne

    RECRUITING

    Melbourne, Victoria, 3065, Australia

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