Could fasting one day a week reshape your metabolism?
NCT ID NCT05722873
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study from the University of Pittsburgh is testing whether fasting one day per week for 12 weeks changes how the body processes fats and maintains bone health. Researchers are enrolling 90 normal-weight or overweight adults aged 21-45 who have a family history of type 2 diabetes. The goal is to see if fasting's benefits go beyond just weight loss.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Fasting (one day per week for 12 weeks)
What this could lead to
If successful, this could help clarify whether intermittent fasting offers metabolic benefits beyond weight loss, potentially guiding future dietary recommendations for diabetes prevention.
What could go wrong
This is an early-stage observational study with only 90 participants, so results may not apply broadly. Fasting could also negatively affect bone health, which the study is monitoring.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Pittsburgh
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
Contact Email: •••••@•••••