Race against time: new drug aims to halt stroke damage in critical first two hours

NCT ID NCT03496883

Ongoing Disease control Sponsor: Joseph Broderick, MD Source: ClinicalTrials.gov ↗

Summary

This large, late-stage trial is testing if a medication that helps blood clot, called rFVIIa, can improve recovery for people who have a stroke caused by bleeding in the brain. The key is giving the drug within two hours of the stroke starting, with the goal of stopping the bleed from getting worse. About 860 participants worldwide will receive either the study drug or a placebo, along with standard care, to see if it leads to better long-term outcomes.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Arnau de Vilanova University Hospital

Lleida, Catalonia, 25198, Spain
Barnes Jewish Hospital

St Louis, Missouri, 63110, United States
Bellvitge University Hospital,

L'Hospitalet de Llobregat, Barcelona, 08907, Spain
Central DuPage Hospital

Winfield, Illinois, 60190, United States
Charite University Medicine Berlin

Berlin, Germany
Clinic Frankfurt Hoechst

Frankfurt am Main, Hesse, Germany
Gifu University Hospital

Gifu, Japan
Girona University Hospital

Girona, Catalonia, 17007, Spain
Grady Memorial Hospital

Atlanta, Georgia, 30303, United States
Hamilton General Hospital

Hamilton, Ontario, L8L 2X2, Canada
Henry Ford Hospital

Detroit, Michigan, 48208, United States
Hospital Universitari Germans Trias i Pujol

Badalona, Barcelona, 21A 08916, Spain
Iwate Prefectural Central Hospital

Morioka, Japan
Japanese Red Cross Kyoto Daini Hospital

Kyoto, Japan
Jichi Medical University Hospital

Shimotsuke, Japan
John Radcliffe Hospital

Oxford, Oxfordshire, OX3 9DU, United Kingdom
KMU University Hospital

Osaka, Japan
Kagoshima City Hospital

Kagoshima, Japan
Kaiser Permanente Baldwin Park Medical Center

Baldwin Park, California, 91706, United States
Kaiser Permanente Downey Medical Center

Downey, California, 90242, United States
Kaiser Permanente Fontana Medical Center

Fontana, California, 92335, United States
Kaiser Permanente Los Angeles Medical Center

Los Angeles, California, 90027, United States
Kaiser Permanente Riverside Medical Center

Riverside, California, 92505, United States
Kaiser Permanente South Bay Medical Center

Harbor City, California, 90710, United States
Kaiser Permanente West Los Angeles Medical Center

Los Angeles, California, 90034, United States
Kobe City Medical Center General Hospital

Kobe, Japan
Kyorin University Hospital

Tokyo, Japan
Kyushu Medical Center

Fukuoka, Japan
M Health Fairview Ridges Hospital,

Burnsville, Minnesota, 55337, United States
M Health Fairview Southdale Hospital

Edina, Minnesota, 55435, United States
M Health Fairview St. John's Hospital

Maplewood, Minnesota, 55109, United States
M Health Fairview University of Minnesota Medical Center Hospital,

Minneapolis, Minnesota, 55455, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Mayo Clinic

Jacksonville, Florida, 32224, United States
Mayo Clinic Saint Marys Campus

Rochester, Minnesota, 55902, United States
Medical University of South Carolina University Hospital

Charleston, South Carolina, 29425, United States
Memorial Hermann Memorial City Medical Center

Houston, Texas, 77024, United States
Memorial Hermann-Texas Medical Center

Houston, Texas, 77030, United States
Mills Peninsula Medical Center

Burlingame, California, 94010, United States
Mount Sinai West

New York, New York, 10019, United States
NHO Osaka National Hospital

Osaka, Japan
Nakamura Memorial Hospital

Sapporo, Japan
National Cerebral and Cardiovascular Center

Suita, Osaka, 564-8565, Japan
Niigata City General Hospital

Niigata, Japan
North Shore University Hospital

Manhasset, New York, 11030, United States
Northwestern Memorial Hospital

Chicago, Illinois, 60611, United States
OSU Wexner Medical Center

Columbus, Ohio, 43210, United States
Ottawa Hospital Research Institute

Ottawa, Ontario, K1H 8L6, Canada
Prisma Health Greenville Memorial Hospital

Greenville, South Carolina, 29605, United States
Providence St. Vincent Medical Center

Portland, Oregon, 97225, United States
Queens Medical Centre

Nottingham, United Kingdom
Riverside Methodist Hospital

Columbus, Ohio, 43214, United States
Ronald Reagan UCLA Medical Center

Los Angeles, California, 90095, United States
Royal Stoke University Hospital

Stoke-on-Trent, Staffordshire, ST4 6QG, United Kingdom
Royal Victoria Infirmary

Newcastle upon Tyne, United Kingdom
San Francisco General Hospital

San Francisco, California, 94110, United States
Santa Creu and Sant Pau Hospital

Barcelona, Catalonia, 08025, Spain
St. John Medical Center

Tulsa, Oklahoma, 74104, United States
St. Joseph's Hospital and Medical Center

Phoenix, Arizona, 85013, United States
St. Michaels Hospital

Toronto, Ontario, M5B 1W8, Canada
Stony Brook University Hospital

Stony Brook, New York, 11794, United States
Sunnybrook Health Sciences Center

Toronto, Ontario, M4N 3M5, Canada
Temple University Hospital

Philadelphia, Pennsylvania, 19140, United States
The Mount Sinai Hospital

New York, New York, 10029, United States
The Queen's Medical Center

Honolulu, Hawaii, 96813, United States
Toledo Hospital

Toledo, Ohio, 43606, United States
Toranomon Hospital

Tokyo, Japan
UC Davis Medical Center

Sacramento, California, 95817, United States
UC Irvine Medical Center,

Orange, California, 92868, United States
UCSD Health La Jolla

La Jolla, California, 92037, United States
UCSD Medical Center - Hillcrest Hospital

San Diego, California, 92103, United States
UF Health Shands Hospital

Gainesville, Florida, 32608, United States
UMass Memorial Medical Center

Worcester, Massachusetts, 01605, United States
University Hospital Augsburg

Augsburg, 86156, Germany
University Hospital Heidelberg

Heidelberg, Baden-Wurttemberg, 69120, Germany
University Hospital Tuebingen

Tübingen, 72076, Germany
University of Alabama Hospital

Birmingham, Alabama, 35233, United States
University of Alberta Hospital

Edmonton, Alberta, AB T6G 2B7, Canada
University of Calgary - Foothills Medical Centre

Calgary, Alberta, Canada
University of Chicago Medical Center

Chicago, Illinois, 60637, United States
University of Cincinnati Medical Center

Cincinnati, Ohio, 45229, United States
University of Montreal Hospital

Montreal, Quebec, H2X 3E4, Canada
University of Utah Healthcare

Salt Lake City, Utah, 84132, United States
VCU Medical Center

Richmond, Virginia, 23219, United States
Vall d'Hebron University Hospital (VHUH)

Horta, Barcelona, Spain
Vancouver General Hospital

Vancouver, British Columbia, V5Z 1M9, Canada
Wake Forest Baptist Medical Center

Winston-Salem, North Carolina, 27157, United States
WellStar Kennestone Hospital

Marietta, Georgia, 30060, United States

Conditions

Explore the condition pages connected to this study.

INTRACEREBRAL HEMORRHAGE