Personalized cell therapy takes on Lung-Lining tumors

NCT ID NCT07192900

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial is testing a new immunotherapy called Fast TILs for people with metastatic cancer or mesothelioma that has spread to the pleura (the lining around the lungs). The treatment uses the patient's own immune cells collected from their pleural fluid, which are multiplied in a lab and then delivered back into the chest through a catheter, along with a low dose of Interleukin-2. The main goals are to see if this approach is safe and if the personalized cell product can be made reliably. Only 10 participants will be enrolled, and the active treatment lasts about three weeks, with follow-up over five years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fast TILs (immune cells from the patient's own pleural fluid) plus Interleukin-2

What this could lead to

If it works, this could point toward a new treatment option for people with cancer that has spread to the lining of the lungs.

What could go wrong

This is a very early, first-in-human trial with only 10 participants. The treatment may not work, and there are unknown risks, including serious side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

malignant mesothelioma Mesothelioma, Malignant Pleural Effusion, Malignant

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AHN West Penn Hospital

    RECRUITING

    Pittsburgh, Pennsylvania, 15224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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