Could a $10 heartburn pill prevent sickle cell pain crises?

NCT ID NCT05084521

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 21 times

Summary

This study tested whether famotidine, a common heartburn medicine, can lower a blood marker linked to painful blockages in children with sickle cell disease. Thirty children aged 1 to 17 took the drug for 29 days. The goal was to see if it reduces P-selectin, a protein involved in cell clumping, which could lead to fewer pain crises.

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Contacts and locations

Locations

  • Necker - Enfants malades Hospital; Department of Pediatrics and Infectious Diseases

    Paris, 75015, France

Conditions

Explore the condition pages connected to this study.