Eye tracking could unlock new biomarker for angelman syndrome

NCT ID NCT06737718

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study will use eye tracking to measure how children with Angelman syndrome look at social and non-social images. Researchers hope to identify abnormalities in social perception that could serve as a biomarker for future treatment trials. The study includes 40 children with Angelman syndrome and 20 healthy controls, all aged 3 to 17.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, eye tracking could become a reliable biomarker to measure social improvements in future Angelman syndrome clinical trials.
What could go wrong
This is an early observational study with only 60 participants, so results may not apply to all children with Angelman syndrome. Eye tracking may not detect meaningful differences.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Necker-Enfants Malades

    RECRUITING

    Paris, 75015, France

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