Experimental eye drops for GVHD dry eye show early promise but trial stops short
NCT ID NCT06495307
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new eye drop (rhPRG4) in 3 adults with moderate to severe dry eye from chronic graft-versus-host disease (GVHD), a complication of bone marrow transplants. The goal was to see if the drops safely improve dryness and eye surface damage. The trial was terminated early, so results are limited.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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OTA
Brisbane, Queensland, Australia
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Sydney Eye Hospital
Sydney, New South Wales, Australia
More trials for these conditions
Other studies related to the condition(s) this trial covers.