New eye drop offers hope for dry eye in transplant patients

NCT ID NCT07118254

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental eye drop (rhPRG4) to see if it safely eases dry eye symptoms in people with ocular graft-versus-host disease (oGVHD), a complication after bone marrow transplant. About 15 adults with moderate to severe dry eye will receive both the active drop and a placebo in random order, each for 28 days. The goal is to measure improvements in eye staining and symptoms like dryness and burning.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OCULAR GRAFT-VERSUS-HOST DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • OTA

    RECRUITING

    Brisbane, Queensland, Australia

  • Royal Melbourne Hospital

    RECRUITING

    Melbourne, Victoria, Australia

  • Sydney Eye Hospital

    NOT_YET_RECRUITING

    Sydney, New South Wales, Australia

More trials for these conditions

Other studies related to the condition(s) this trial covers.