New eye injection could shrink metastatic tumors in the eye
NCT ID NCT06643884
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 2 trial tests a drug called belzupacap sarotalocan (AU-011) for people whose cancer has spread to the choroid, the layer of blood vessels in the eye. The drug is injected into the eye and then activated with a laser. The study aims to see if it is safe and can shrink or control the tumor. It involves 24 participants and will test different doses.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- belzupacap sarotalocan (AU-011) with laser activation
- What this could lead to
- If it works, this could offer a new treatment option for people with eye cancer that has spread from another part of the body, potentially controlling tumor growth without removing the eye.
- What could go wrong
- This is an early Phase 2 trial with only 24 people, so results may not apply to everyone. The treatment involves a laser and injection into the eye, which carries risks like infection or vision changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Bascom Palmer Eye Institute
RECRUITINGMiami, Florida, 33136, United States
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Byers Eye Institute at Stanford University
RECRUITINGPalo Alto, California, 94303, United States
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Cleveland Clinic, Cole Eye Institute
NOT_YET_RECRUITINGCleveland, Ohio, 44195, United States
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Kellogg Eye Center
RECRUITINGAnn Arbor, Michigan, 48105, United States
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Massachusetts Eye and Ear
RECRUITINGBoston, Massachusetts, 02114, United States
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Mayo Clinic
NOT_YET_RECRUITINGRochester, Minnesota, 55905, United States
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Retina Consultants of Texas
RECRUITINGBellaire, Texas, 77401, United States
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Shields and Shields, PC
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
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Tennessee Retina, PC
RECRUITINGNashville, Tennessee, 37203, United States
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University of Washington
RECRUITINGSeattle, Washington, 98104, United States
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