New hope for chronic dry eye from Graft-Versus-Host disease: expanded access to d-MAPPS eye drops
NCT ID NCT07210619
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This expanded access program makes an investigational eye drop called d-MAPPS available to adults with chronic ocular graft-versus-host disease (oGVHD), a painful dry eye condition that can occur after a stem cell or bone marrow transplant. The treatment is a protein-based solution derived from donor cells. Participants must have moderate to severe symptoms and be in stable overall health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
d-MAPPS ophthalmic solution (a protein-based eye drop derived from donor cells)
What this could lead to
If successful, this expanded access program could provide a new treatment option for people with chronic dry eye caused by graft-versus-host disease.
What could go wrong
This is an expanded access program, not a full clinical trial, so data on effectiveness and safety is still limited. The treatment may not work for everyone and could have side effects.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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