Tiny particles in lung fluid may predict cancer treatment success

This study aims to see if exosomes—tiny particles released by cells—found in blood and lung fluid can help predict how well treatment works in people with advanced non-small cell lung cancer that has spread to the lining of the lung. Researchers will collect samples from 100 patients before and during standard therapy (like immunotherapy or chemotherapy) and compare the exosome RNA patterns to treatment response. The goal is to find a way to personalize treatment decisions without adding new drugs or procedures.