Brain speed test could transform sickle cell care
NCT ID NCT07168447
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study examines how regular blood transfusions (exchange transfusions) affect thinking speed in adults with severe sickle cell disease. Researchers will test 85 participants remotely using a simple symbol-matching task and other cognitive assessments at different points in their transfusion cycle. The goal is to see if processing speed can be a reliable marker for monitoring brain health in this condition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors use a simple thinking-speed test to monitor brain health in sickle cell patients and guide future treatments.
- What could go wrong
- This is an early observational study, not a treatment trial. It may not find clear links, and results might not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Assistance Publique - Hôpitaux de Paris Hôpital Avicenne
Bobigny, Île-de-France Region, 93000, France
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Assistance Publique - Hôpitaux de Paris Hôpital Necker
Paris, Île-de-France Region, 75015, France
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Centre Hospitalier Saint-Denis
Saint-Denis, Île-de-France Region, 93200, France
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GHU Paris Psychiatrie et Neurosciences - Hôpital Sainte-Anne
Paris, Île-de-France Region, 75014, France
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Hôpital Henri Mondor
Créteil, Île-de-France Region, 94000, France
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Hôpital Kremlin-Bicêtre
Le Kremlin-Bicêtre, Île-de-France Region, 94 275, France