Brain speed test could transform sickle cell care

NCT ID NCT07168447

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study examines how regular blood transfusions (exchange transfusions) affect thinking speed in adults with severe sickle cell disease. Researchers will test 85 participants remotely using a simple symbol-matching task and other cognitive assessments at different points in their transfusion cycle. The goal is to see if processing speed can be a reliable marker for monitoring brain health in this condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors use a simple thinking-speed test to monitor brain health in sickle cell patients and guide future treatments.

What could go wrong

This is an early observational study, not a treatment trial. It may not find clear links, and results might not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DREPANOCYTOSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

anxiety disorder Depression Fatigue sickle cell disease Sickle Cell Trait

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Assistance Publique - Hôpitaux de Paris Hôpital Avicenne

    Bobigny, Île-de-France Region, 93000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Assistance Publique - Hôpitaux de Paris Hôpital Necker

    Paris, Île-de-France Region, 75015, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Hospitalier Saint-Denis

    Saint-Denis, Île-de-France Region, 93200, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • GHU Paris Psychiatrie et Neurosciences - Hôpital Sainte-Anne

    Paris, Île-de-France Region, 75014, France

  • Hôpital Henri Mondor

    Créteil, Île-de-France Region, 94000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Kremlin-Bicêtre

    Le Kremlin-Bicêtre, Île-de-France Region, 94 275, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••