Personalized vaccine trial aims to boost immune attack on advanced skin cancer

NCT ID NCT05309421

Summary

This study is testing whether adding a personalized cancer vaccine called EVX-01 to a standard immunotherapy drug (pembrolizumab) can better control advanced melanoma that cannot be surgically removed. It involves about 17 adults with stage III or IV melanoma who have not yet received certain types of immunotherapy. Patients receive the standard drug first, then start the personalized vaccine injections after 12 weeks to try to train their immune system to fight their specific cancer.

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Contacts and locations

Locations

  • Divisione di Oncologia Medica del Melanoma

    Milan, Italy

  • Instituto Nazionale Tumori IRCCS Fondazione

    Naples, Italy

  • Melanoma Institute Australia

    Wollstonecraft, New South Wales, 2065, Australia

  • One Clinical Research

    Nedlands, Western Australia, 6009, Australia

Conditions

Explore the condition pages connected to this study.