New hope for mesothelioma patients: experimental combo enters final testing

NCT ID NCT06097728

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Sep 30, 2025 · Last updated May 16, 2026 · Updated 28 times

Summary

This study tests a new drug called volrustomig combined with chemotherapy against standard treatments for people with advanced pleural mesothelioma that cannot be removed by surgery. About 825 adults will take part worldwide. The goal is to see if the new combination helps people live longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

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WITHDRAWN

Phoenix, Arizona, 85054, United States
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Duarte, California, 91010, United States
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Santa Rosa, California, 95403, United States
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Aurora, Colorado, 80045, United States
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Jacksonville, Florida, 32224, United States
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Atlanta, Georgia, 30322, United States
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Chicago, Illinois, 60637, United States
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Baltimore, Maryland, 21231, United States
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Rochester, Minnesota, 55905, United States
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St Louis, Missouri, 63110, United States
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East Brunswick, New Jersey, 08816, United States
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Commack, New York, 11725, United States
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Valhalla, New York, 10595, United States
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Cleveland, Ohio, 44111, United States
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Cleveland, Ohio, 44124, United States
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Cleveland, Ohio, 44195, United States
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Columbus, Ohio, 43210, United States
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Independence, Ohio, 44131, United States
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Portland, Oregon, 97213, United States
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Portland, Oregon, 97225, United States
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Portland, Oregon, 97239, United States
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Philadelphia, Pennsylvania, 19104, United States
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Houston, Texas, 77030, United States
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Fairfax, Virginia, 22031, United States
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Chermside, 4032, Australia
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Clayton, 3168, Australia
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Melbourne, 3000, Australia
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Nedlands, 6009, Australia
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Westmead, 2145, Australia
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Anderlecht, 1070, Belgium
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Antwerp, 2020, Belgium
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COMPLETED

Ghent, 9000, Belgium
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Hasselt, 3500, Belgium
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Leuven, 3000, Belgium
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Sint-Niklaas, 9100, Belgium
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Barretos, 14784-400, Brazil
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Fortaleza, 60336-045, Brazil
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João Pessoa, 58013-140, Brazil
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Porto Alegre, 91350-200, Brazil
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Rio de Janeiro, 22281-100, Brazil
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Santo André, 09060-650, Brazil
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São Paulo, 01246-000, Brazil
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Edmonton, Alberta, T6G 1Z2, Canada
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Hamilton, Ontario, L8V 1C3, Canada
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London, Ontario, N6A 5W9, Canada
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Ottawa, Ontario, K1H 8L6, Canada
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Toronto, Ontario, M5G 1X6, Canada
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Montreal, Quebec, H2X 0C1, Canada
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Québec, Quebec, G1V 4G5, Canada
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Beijing, 100142, China
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Beijing, 100210, China
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Changchun, 130021, China
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Changsha, 410013, China
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Chengdu, 610042, China
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Chongqing, 400030, China
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Guangzhou, 510100, China
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Hangzhou, 310022, China
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Harbin, 150049, China
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Kunming, 650118, China
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Lanzhou, 730000, China
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Nanchang, 330006, China
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Ningbo, 315100, China
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Qingdao, 266003, China
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Shandong, China
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Shanghai, 200032, China
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Shenyang, 110044, China
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Taiyuan, 030000, China
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Taiyuan, 030032, China
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Tianjin, 300050, China
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Tianjin, 300060, China
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Wuhan, 430030, China
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COMPLETED

Xi'an, 710061, China
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Zhengzhou, 450008, China
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Zhengzhou, 450052, China
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Aarhus N, 8200, Denmark
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Copenhagen, 2100, Denmark
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Brest, 29200, France
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Créteil, 94010, France
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Le Mans, 72037, France
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Lille, 59037, France
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Lyon, 69373, France
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Marseille, 13015, France
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Montpellier, 34298, France
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Paris, 75877, France
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Rouen, 76031, France
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Saint-Herblain, 44800, France
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Strasbourg, 67091, France
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Toulouse, 31059, France
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Berlin, 13125, Germany
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Berlin, 14109, Germany
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Bochum, 44791, Germany
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Cologne, 51109, Germany
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Essen, 45122, Germany
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Essen, 45130, Germany
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Gauting, 82131, Germany
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Georgsmarienhütte, 49124, Germany
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Großhansdorf, 22927, Germany
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Hamburg, 21075, Germany
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Heidelberg, 69126, Germany
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Kiel, 24105, Germany
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Münster, 48153, Germany
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Regensburg, 93049, Germany
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Alessandria, 15100, Italy
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Bari, 70124, Italy
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Bergamo, 24125, Italy
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Milan, 20141, Italy
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Monza, 20052, Italy
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Orbassano, 10043, Italy
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Padova, 35128, Italy
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Parma, 43100, Italy
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Rozzano, 20089, Italy
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Varese, 21100, Italy
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Amagasaki-shi, 660-8550, Japan
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Hakodate-shi, 040-8611, Japan
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Hiroshima, 734-8551, Japan
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Kitaadachi-gun, 362-0806, Japan
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Kitakyushu-shi, 807-8555, Japan
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ACTIVE_NOT_RECRUITING

Matsuyama, 791-0280, Japan
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ACTIVE_NOT_RECRUITING

Nagoya, 466-8560, Japan
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Nishinomiya-shi, 663-8501, Japan
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Okayama, 702-8055, Japan
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Osakasayama-shi, 589-8511, Japan
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Tokyo, 104-0045, Japan
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Ube-shi, 755-0241, Japan
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Amsterdam, 1066CX, Netherlands
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Eindhoven, 5623EJ, Netherlands
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Rotterdam, 3015 GD, Netherlands
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COMPLETED

Lørenskog, 1478, Norway
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ACTIVE_NOT_RECRUITING

Oslo, 450, Norway
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WITHDRAWN

Bydgoszcz, 85-796, Poland
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Bystra, 43-360, Poland
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Olsztyn, 10-357, Poland
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Poznan, 60-569, Poland
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Rzeszów, 35-241, Poland
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Warsaw, 02-781, Poland
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Cape Town, 7570, South Africa
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eManzimtoti, 4126, South Africa
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Johannesburg, 2013, South Africa
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Johannesburg, 2193, South Africa
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Kimberly, 8301, South Africa
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Polokwane, 0700, South Africa
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Pretoria, 0002, South Africa
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Pretoria, 0081, South Africa
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Cheongju-si, 28644, South Korea
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Seoul, 03080, South Korea
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Seoul, 06351, South Korea
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Seoul, 06591, South Korea
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WITHDRAWN

Ulsan, 44033, South Korea
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Barakaldo, 48903, Spain
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Barcelona, 8035, Spain
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Madrid, 28041, Spain
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Oviedo, 33011, Spain
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Baden, CH-5405, Switzerland
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Basel, 4031, Switzerland
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Bern, 3010, Switzerland
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Fribourg, 1700, Switzerland
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Sankt Gallen, 9007, Switzerland
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Kaohsiung City, 80756, Taiwan
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Taichung, 40705, Taiwan
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Tainan, 70403, Taiwan
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Taipei, 10002, Taiwan
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Taoyuan, 333, Taiwan
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WITHDRAWN

Adana, 01060, Turkey (Türkiye)
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ACTIVE_NOT_RECRUITING

Ankara, 06280, Turkey (Türkiye)
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Ankara, 06800, Turkey (Türkiye)
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Diyarbakır, 21280, Turkey (Türkiye)
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Izmir, 35110, Turkey (Türkiye)
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Cambridge, CB20QQ, United Kingdom
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WITHDRAWN

Cardiff, Wales, CF5 6NF, United Kingdom
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Leeds, LS9 7TF, United Kingdom
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Leicester, LE1 5WW, United Kingdom
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London, NW1 2PG, United Kingdom
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London, SE1 9RT, United Kingdom
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London, SW3 6JJ, United Kingdom
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Manchester, M23 9LT, United Kingdom
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Newcastle upon Tyne, NE2 4HH, United Kingdom
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Portsmouth, PO6 3LY, United Kingdom
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Taunton, TA1 5DA, United Kingdom

Conditions

Explore the condition pages connected to this study.

UNRESECTABLE PLEURAL MESOTHELIOMA