New heart valve tested in hundreds of patients shows promise for safer treatment

NCT ID NCT03417011

Summary

This study tested the Evolut PRO system, a replacement heart valve, in 638 patients with severe aortic valve stenosis who were at high or intermediate risk for open-heart surgery. The goal was to see how safe and effective the valve is in real-world hospital settings over five years. Researchers tracked survival, valve performance, complications, and patients' quality of life.

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Contacts and locations

Locations

  • AOU Presidio Gaspare Rodolico Policlinico

    Catania, Italy

  • Asklepios Klinik St. Georg

    Hamburg, Germany

  • Azienda Ospedaliera Ospedale Niguarda Cà Granda

    Milan, Italy

  • Azienda Ospedaliera Spedali Civili di Brescia

    Brescia, Italy

  • Azienda Ospedaliero Universitaria Pisana - Stabilimento di Cisanello

    Pisa, Italy

  • CHU Bordeaux

    Bordeaux, France

  • CHU de Liège - Hôpital du Sart Tilman

    Liège, Belgium

  • Catharina Ziekenhuis Eindhoven

    Eindhoven, Netherlands

  • Clinique Pasteur

    Toulouse, France

  • Complejo Hospitalario Universitario de Santiago de Compostela

    Santiago de Compostela, Spain

  • Deutsches Herzzentrum Berlin

    Berlin, Germany

  • Deutsches Herzzentrum München Klinik an der TU München

    Munich, Germany

  • Erasmus Medisch Centrum

    Rotterdam, Netherlands

  • Hadassah Medical Organisation

    Jerusalem, Israel

  • Herz- und Diabeteszentrum NRW - Ruhr-Universität Bochum

    Bad Oeynhausen, Germany

  • Herzzentrum Dresden GmbH Universitätsklinik

    Dresden, Germany

  • Herzzentrum Leipzig GmbH

    Leipzig, Germany

  • Hospital Universitario Central de Asturias

    Oviedo, Spain

  • Hospital Universitario Virgen de la Victoria

    Málaga, Spain

  • Hôpital Henri Mondor

    Créteil, France

  • IRCCS Policlinico San Donato

    Milan, Italy

  • Inselspital - Universitätsspital

    Bern, Switzerland

  • LKH - Universitätsklinikum

    Graz, Austria

  • Onze Lieve Vrouwe Gasthuis

    Amsterdam, Netherlands

  • Oslo Universitetssykehus-Ullevål

    Oslo, Norway

  • Rabin Medical Center - Beilinson Hospital

    Petah Tikva, Israel

  • Rigshospitalet

    Copenhagen, Denmark

  • Royal Victoria Hospital - Belfast Health and Social Care Trust

    Belfast, United Kingdom

  • SANA Herzchirurgie Stuttgart GmbH

    Stuttgart, Germany

  • Sana-Herzzentrum Cottbus GmbH

    Cottbus, Germany

  • St. George's Hospital

    London, United Kingdom

  • The Royal Wolverhampton Hospitals NHS - New Cross Hospital

    Wolverhampton, United Kingdom

  • Turun Yliopistollinen Keskussairaala

    Turku, Finland

  • Universitair Ziekenhuis Antwerpen

    Antwerp, Belgium

  • University Medical Centre

    Ljubljana, Slovenia

  • Universitätsklinikum Bonn

    Bonn, Germany

  • Universitätsklinikum Düsseldorf

    Düsseldorf, Germany

  • Universitätsklinikum Essen

    Essen, Germany

  • Universtitätsspital Zürich

    Zurich, Switzerland

Conditions

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