Could a heart drug tame pancreatitis? small trial aims to find out

NCT ID NCT07388420

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests whether adding evolocumab (a drug used for high cholesterol) to standard care can quickly lower very high triglycerides in people with pancreatitis caused by high triglycerides. The trial will enroll 40 adults and measure triglyceride levels after 3 and 7 days. The goal is to see if this combination can reduce the risk of severe pancreatitis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Evolocumab (Repatha)

What this could lead to

If it works, this could offer a new way to quickly lower triglycerides and prevent severe complications in pancreatitis patients.

What could go wrong

This is a small, early pilot study with only 40 participants. The effect on triglycerides is uncertain, and it may not improve outcomes or be safe for all.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Gastroenterology, General Hospital of Northern Theater Command (formerly called General Hospital of Shenyang Military Area)

    RECRUITING

    Shenyang, Liaoning, 110840, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••