New cancer vaccine aims to fight advanced tumors when other treatments fail

NCT ID NCT06541639

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a cancer vaccine called EVM16, either by itself or combined with an immune-boosting drug (tislelizumab), in people with advanced or recurrent solid tumors that have not responded to standard treatments. The main goals are to find a safe dose and see if the vaccine triggers an immune response against the cancer. The trial involves about 78 participants and will monitor side effects and any tumor shrinkage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

EVM16 (cancer vaccine) and tislelizumab (anti-PD-1 antibody)

What this could lead to

If successful, this approach could offer a new treatment option for people with advanced solid tumors who have run out of standard therapies.

What could go wrong

This is an early-phase trial with a small number of participants, so the vaccine may not prove effective or may cause unexpected side effects. The results may not apply to all tumor types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Cancer Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100142, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, Shanghai Municipality, 200135, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••