New trial aims to boost survival in severe shock by relieving heart pressure early
NCT ID NCT07027202
First seen Apr 25, 2026 · Last updated Jun 16, 2026 · Updated 11 times
Summary
This study tests whether adding a balloon pump early to relieve pressure on the left ventricle improves outcomes for people in severe cardiogenic shock who are already on a heart-lung machine (VA-ECMO). About 298 adults will be randomly assigned to early preventive unloading or standard care with rescue unloading only if needed. The goal is to see if early intervention reduces death, complications, and time on life support.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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APHP - hôpital Pitié-Salpêtrière
RECRUITINGParis, 75013, France
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APHP - hôpital Pitié-Salpêtrière
NOT_YET_RECRUITINGParis, 75013, France
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APHP - hôpital Pitié-Salpêtrière
NOT_YET_RECRUITINGParis, 75013, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHRU Nancy - hôpitaux de brabois
NOT_YET_RECRUITINGVandœuvre-lès-Nancy, 54500, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Clermont-Ferrand - Site Gabriel Montpied
NOT_YET_RECRUITINGClermont-Ferrand, 63000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Henri Mondor
NOT_YET_RECRUITINGCréteil, 94000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Cardiologique
NOT_YET_RECRUITINGLille, 59000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Européen Georges Pompidou
NOT_YET_RECRUITINGParis, 75015, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Rangueil
NOT_YET_RECRUITINGToulouse, 31059, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital du Pontchaillou
NOT_YET_RECRUITINGRennes, 35033, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nouvel Hôpital Civil
NOT_YET_RECRUITINGStrasbourg, 67000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nouvel hôpital civil
NOT_YET_RECRUITINGStrasbourg, 67000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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