Could a cool eye zap away chronic pain?

NCT ID NCT07059754

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This small study tests a device that cools the eye surface to see if it helps people with chronic eye pain. Five participants will get a single 4-minute cold treatment and be followed for 12 weeks. Researchers will take pictures of the eye's nerves and collect tear samples to look for changes in inflammation and structure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ETX-4143 topical ophthalmic cooling device

What this could lead to

If it works, this could point toward a non-drug way to ease chronic eye pain by cooling the eye surface.

What could go wrong

This is a very early, tiny study with only 5 people. It is designed to see if the device is safe and worth studying further, not to prove it works. The results may not apply to everyone with eye pain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Eye Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sunshine Eye Surgeons

    RECRUITING

    Melbourne, Victoria, 3021, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••