New hope for seniors with stubborn depression: esketamine spray vs aripiprazole pill
NCT ID NCT07153406
First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 23 times
Summary
This study tests whether esketamine nasal spray works better than aripiprazole pills for older adults (60-74 years) whose depression hasn't improved with standard antidepressants. Both treatments are added to the patient's current antidepressant. The main goal is to see if symptoms improve or go away after 8 weeks. About 220 participants will take part across multiple centers.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centro Sociosanitario Hermanas Hospitalarias de Palencia
Palencia, 34004, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Clínica Psiquiátrica Padre Menni
Pamplona, Navarre, 31014, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Corporacion Sanitaria Parc Tauli
Sabadell, 08208, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Benito Menni y Fidmag Hermanas Hospitalarias
Barcelona, 08830, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital De La Santa Creu i Sant Pau
Barcelona, 08041, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Mare de Déu de La Mercè
Barcelona, 08042, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Sagrat Cor. Martorell
Barcelona, 08760, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario Virgen del Rocio
Seville, 41013, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Vall d'Hebron
Barcelona, 08014, Spain
Conditions
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