New brain drain device could help older adults walk better

NCT ID NCT06498960

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new device called the eShunt System for treating normal pressure hydrocephalus, a condition that causes trouble walking, thinking, and bladder control in older adults. The device drains extra fluid from the brain through a small tube. Researchers will compare it to the standard treatment (VP shunt) in 230 people aged 60 and older. The main goal is to see if walking improves after 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

eShunt System (a device that drains fluid from the brain)

What this could lead to

If successful, this device could offer a less invasive alternative to standard shunts, improving walking and daily function in older adults with normal pressure hydrocephalus.

What could go wrong

This is a pivotal trial, but results are not yet available. The device may not improve symptoms as hoped, and risks include infection, bleeding, or device malfunction.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

normal pressure hydrocephalus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Advocate Lutheran General Hospital

    Park Ridge, Illinois, 60068, United States

  • Albany Medical Center

    Albany, New York, 12208, United States

  • Baptist Medical Center - Jacksonville

    Jacksonville, Florida, 32207, United States

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Clinica La Sagrada Familia

    Buenos Aires, C1426B, Argentina

  • Cooper Neurological Institute

    Camden, New Jersey, 08103, United States

  • Henry Ford Health

    West Bloomfield, Michigan, 48322, United States

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Indiana University

    Indianapolis, Indiana, 46202, United States

  • Lenox Hill Hospital

    New York, New York, 10075, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Milton S. Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • Northwell Health

    Manhasset, New York, 11030, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • St. Michael's Hospital

    Toronto, Ontario, M5C 2W6, Canada

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • University at Buffalo Neurosurgery

    Buffalo, New York, 14203, United States

  • University of Calgary - Foothills Medical Centre

    Calgary, Alberta, T2N 4N1, Canada

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

  • University of Kentucky Research Foundation

    Lexington, Kentucky, 40506, United States

  • University of Rochester Medical Center

    Rochester, New York, 14642, United States

  • University of South Florida

    Tampa, Florida, 33606, United States

  • University of Southern California

    Los Angeles, California, 90033, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • Virginia Commonwealth University

    Richmond, Virginia, 23298, United States

  • Weill Cornell Medicine

    New York, New York, 10065, United States

  • Yale University

    New Haven, Connecticut, 06511, United States