Heart failure drug combo study aims to improve fluid control
NCT ID NCT04438213
First seen Nov 01, 2025 · Last updated Jun 03, 2026 · Updated 31 times
Summary
This study tests whether adding ertugliflozin (a diabetes drug) or metolazone to standard diuretics helps control fluid buildup and heart failure symptoms better than placebo. About 60 adults with chronic heart failure who already take daily diuretics will participate. Researchers will measure changes in blood volume and sodium excretion over 7 days and 6 weeks.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Yale School of Medicine
RECRUITINGNew Haven, Connecticut, 06510, United States
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