Frostbite breakthrough? new drug trial aims to save limbs
NCT ID NCT07424378
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether the drug epoprostenol, given alongside standard care, can reduce the need for amputation in people with severe frostbite. About 66 adults with grade 2-4 frostbite will receive either the drug or a placebo within 72 hours after rewarming. The goal is to see if the drug helps save fingers and toes by improving blood flow.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Colorado, Denver
Aurora, Colorado, 80045, United States
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University of Colorado, Denver
Aurora, Colorado, 80045, United States
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