Epidural volume may change pain relief quality in labor
NCT ID NCT07684365
First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time
Summary
This trial investigates whether the volume and concentration of medication given through an epidural affect how well it relieves labor pain and what side effects occur. Pregnant women at 36 weeks or more, in early labor or being induced, receive the same dose of bupivacaine and fentanyl but in different volumes. Researchers track how often women need extra pain relief to see which approach works best.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine and fentanyl
- What this could lead to
- If it works, this could help tailor epidural doses to improve pain relief and reduce side effects for women in labor.
- What could go wrong
- This is a small, single-center study focused on short-term outcomes, so results may not apply to all hospitals or patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 18 years of age or older * Gestational age of 36 weeks or greater * American Society of Anesthesiology physical status 2 * Induction of labor or early labor (cervical dilation \< 6cm) * Singleton gestation * Vertex presentation Exclusion Criteria: * Preeclampsia * Receiving magnesium sulfate * Having received narcotics within 4 hours * Multiple gestation * Major fetal anomalies or demise * Previous spine surgery * Known major spine pathology * Substance use disorder
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
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