New hope for rare lung infection: epetraborole trial begins

NCT ID NCT07301320

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called epetraborole for people with a chronic lung infection caused by Mycobacterium abscessus. About 84 adults will take either a low or high dose of the drug or a placebo for 84 days. Researchers will check if symptoms improve and if the infection clears from sputum samples.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

epetraborole

What this could lead to

If it works, this could point toward a new treatment for a hard-to-treat lung infection that currently has limited options.

What could go wrong

This is an early Phase 2 trial with only 84 people, so results may not apply to everyone. The drug may not work better than placebo, and side effects are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

mycobacterial infectious disease Mycobacterium Infections, Nontuberculous pulmonary non-tuberculous mycobacterial infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact