New shot shows promise for tough lymphoma cases

NCT ID NCT07226752

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a new drug called epcoritamab (given as a shot under the skin) against standard chemotherapy for people with diffuse large B-cell lymphoma that has come back or stopped responding to treatment. About 72 participants in China will be randomly assigned to get either the new drug or one of two standard chemo regimens. The main goal is to see if epcoritamab helps people live longer.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma follicular lymphoma high grade B-cell lymphoma with MYC and/ or BCL2 and/or BCL6 rearrangement T-cell/histiocyte rich large B cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Affiliated Hospital of Hebei University

    Baoding, China

  • Beijing Cancer Hospital

    Beijing, China

  • Beijing Tongren Hospital, Capital Medical University

    Beijing, China

  • EC of Union Hospital Tongji Medical College Huazhong University of Science and Technology

    Wuhan, China

  • Guangdong Provincial Peoples Hospital

    Guandong, China

  • Guangxi Medical University Affiliated Tumor Hospital

    Guangxi, China

  • Henan Cancer Hospital

    Zhengzhou, China

  • Hubei Cancer Hospital

    Hubei, China

  • Hunan Cancer Hospital

    Hunan, China

  • Peking University Third Hospital

    Beijing, China

  • Qingdao Central Hospital

    Qingdao, China

  • Shanxi Provincial Cancer Hospital

    Shanxi, China

  • Shengjing Hospital of China Medical University

    Shenyang, China

  • Shenzhen Peoples Hospital

    Shenzhen, China

  • The First Affiliated Hospital of Nanchang University

    Nanchang, China

  • The First Affiliated Hospital of Soochow University

    Suzhou, China

  • The First Affiliated Hospital, Zhejiang University School of Medicine

    Hangzhou, China

  • The First Hospital of Jilin University

    Changchun, China

  • The Second Affiliated Hospital Zhejiang University School of Medicine

    Zhenjiang, China

  • The Second Hospital of Dalian Medical University

    Dalian, China

  • Tianjin Medical University Cancer Institute and Hospital

    Tianjin, China

  • West China Hospital, Sichuan University

    Chengdu, China

  • Yantai Yuhuangding Hospital

    Yantai, China