New hope for rare salivary cancers: repurposed drug enters trial

NCT ID NCT02749903

Ongoing Disease control Sponsor: Alliance for Clinical Trials in Oncology Source: ClinicalTrials.gov ↗

Summary

This study is testing if the drug enzalutamide can shrink tumors in people with advanced salivary gland cancer that has a specific marker (androgen receptor). The trial will enroll about 46 patients to see if the treatment is effective and safe. Enzalutamide is already approved for other cancers but is not yet a standard treatment for this rare disease.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Locations

Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Alaska Breast Care and Surgery LLC

Anchorage, Alaska, 99508, United States
Alaska Oncology and Hematology LLC

Anchorage, Alaska, 99508, United States
Alaska Women's Cancer Care

Anchorage, Alaska, 99508, United States
Allegiance Health

Jackson, Michigan, 49201, United States
Anchorage Associates in Radiation Medicine

Anchorage, Alaska, 98508, United States
Anchorage Oncology Centre

Anchorage, Alaska, 99508, United States
Anchorage Radiation Therapy Center

Anchorage, Alaska, 99504, United States
Armes Family Cancer Center

Findlay, Ohio, 45840, United States
Atrium Medical Center-Middletown Regional Hospital

Franklin, Ohio, 45005-1066, United States
Bay Area Hospital

Coos Bay, Oregon, 97420, United States
Beebe Health Campus

Rehoboth Beach, Delaware, 19971, United States
Beebe Medical Center

Lewes, Delaware, 19958, United States
Benefis Healthcare- Sletten Cancer Institute

Great Falls, Montana, 59405, United States
Big Horn Basin Cancer Center

Cody, Wyoming, 82414, United States
Billings Clinic Cancer Center

Billings, Montana, 59101, United States
Billings Clinic-Cody

Cody, Wyoming, 82414, United States
Blanchard Valley Hospital

Findlay, Ohio, 45840, United States
Bozeman Deaconess Hospital

Bozeman, Montana, 59715, United States
Broadlawns Medical Center

Des Moines, Iowa, 50314, United States
Cancer Care Center at Island Hospital

Anacortes, Washington, 98221, United States
Cancer Care Specialists of Illinois - Decatur

Decatur, Illinois, 62526, United States
Cancer Care Specialists of Illinois-Swansea

Swansea, Illinois, 62226, United States
Cancer Center of Western Wisconsin

New Richmond, Wisconsin, 54017, United States
Cancer Centers of Southwest Oklahoma Research

Lawton, Oklahoma, 73505, United States
Capital Region Southwest Campus

Jefferson City, Missouri, 65109, United States
Carle Cancer Center

Urbana, Illinois, 61801, United States
Carle Physician Group-Effingham

Effingham, Illinois, 62401, United States
Carle Physician Group-Mattoon/Charleston

Mattoon, Illinois, 61938, United States
Carle on Vermilion

Danville, Illinois, 61832, United States
Central Illinois Hematology Oncology Center

Springfield, Illinois, 62702, United States
Centralia Oncology Clinic

Centralia, Illinois, 62801, United States
Chancellor Center for Oncology

Newburgh, Indiana, 47630, United States
Christiana Care Health System-Christiana Hospital

Newark, Delaware, 19718, United States
Christiana Care Health System-Concord Health Center

Chadds Ford, Pennsylvania, 19317, United States
Christiana Care Health System-Wilmington Hospital

Wilmington, Delaware, 19801, United States
Clackamas Radiation Oncology Center

Clackamas, Oregon, 97015, United States
Community Hospital of Anaconda

Anaconda, Montana, 59711, United States
Community Medical Hospital

Missoula, Montana, 59804, United States
Crossroads Cancer Center

Effingham, Illinois, 62401, United States
Dayton Physicians LLC-Atrium

Franklin, Ohio, 45005, United States
Dayton Physicians LLC-Miami Valley South

Centerville, Ohio, 45459, United States
Dayton Physicians LLC-Samaritan North

Dayton, Ohio, 45415, United States
Dayton Physicians LLC-Signal Point

Middletown, Ohio, 45042, United States
Dayton Physicians LLC-Upper Valley

Troy, Ohio, 45373, United States
Dayton Physicians LLC-Wayne

Greenville, Ohio, 45331, United States
Dayton Physicians LLC-Wilson

Sidney, Ohio, 45365, United States
Deaconess Clinic Downtown

Evansville, Indiana, 47713, United States
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
Delaware Clinical and Laboratory Physicians PA

Newark, Delaware, 19713, United States
Fairview Lakes Medical Center

Wyoming, Minnesota, 55092, United States
Fairview Maple Grove Medical Center

Maple Grove, Minnesota, 55369, United States
Fairview Ridges Hospital

Burnsville, Minnesota, 55337, United States
Fairview-Southdale Hospital

Edina, Minnesota, 55435, United States
First Dayton Cancer Care

Kettering, Ohio, 45420, United States
Franciscan Saint Anthony Health-Michigan City

Michigan City, Indiana, 46360, United States
Good Samaritan Hospital - Dayton

Dayton, Ohio, 45406, United States
Great Falls Clinic

Great Falls, Montana, 59405, United States
Greater Dayton Cancer Center

Kettering, Ohio, 45409, United States
Greenville Health System Cancer Institute-Butternut

Greenville, South Carolina, 29605, United States
Greenville Health System Cancer Institute-Easley

Easley, South Carolina, 29640, United States
Greenville Health System Cancer Institute-Eastside

Greenville, South Carolina, 29615, United States
Greenville Health System Cancer Institute-Faris

Greenville, South Carolina, 29605, United States
Greenville Health System Cancer Institute-Greer

Greer, South Carolina, 29650, United States
Greenville Health System Cancer Institute-Laurens

Clinton, South Carolina, 29325, United States
Greenville Health System Cancer Institute-Seneca

Seneca, South Carolina, 29672, United States
Greenville Health System Cancer Institute-Spartanburg

Spartanburg, South Carolina, 29307, United States
Greenville Memorial Hospital

Greenville, South Carolina, 29605, United States
Gundersen Lutheran Medical Center

La Crosse, Wisconsin, 54601, United States
Health Partners Inc

Minneapolis, Minnesota, 55454, United States
Helen F Graham Cancer Center

Newark, Delaware, 19713, United States
Hennepin County Medical Center

Minneapolis, Minnesota, 55415, United States
Henry Ford Cancer Institute?Downriver

Brownstown, Michigan, 48183, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Henry Ford Macomb Hospital-Clinton Township

Clinton Township, Michigan, 48038, United States
Henry Ford Medical Center-Columbus

Novi, Michigan, 48377, United States
Henry Ford Medical Center-Fairlane

Dearborn, Michigan, 48126, United States
Henry Ford West Bloomfield Hospital

West Bloomfield, Michigan, 48322, United States
Illinois CancerCare-Bloomington

Bloomington, Illinois, 61704, United States
Illinois CancerCare-Canton

Canton, Illinois, 61520, United States
Illinois CancerCare-Carthage

Carthage, Illinois, 62321, United States
Illinois CancerCare-Eureka

Eureka, Illinois, 61530, United States
Illinois CancerCare-Galesburg

Galesburg, Illinois, 61401, United States
Illinois CancerCare-Kewanee Clinic

Kewanee, Illinois, 61443, United States
Illinois CancerCare-Macomb

Macomb, Illinois, 61455, United States
Illinois CancerCare-Ottawa Clinic

Ottawa, Illinois, 61350, United States
Illinois CancerCare-Pekin

Pekin, Illinois, 61554, United States
Illinois CancerCare-Peoria

Peoria, Illinois, 61615, United States
Illinois CancerCare-Peru

Peru, Illinois, 61354, United States
Illinois CancerCare-Princeton

Princeton, Illinois, 61356, United States
Indu and Raj Soin Medical Center

Beavercreek, Ohio, 45431, United States
Inova Fairfax Hospital

Falls Church, Virginia, 22042, United States
Inova Fairfax Hospital-Woodburn Infusion Clinic

Annandale, Virginia, 22003, United States
Iowa Lutheran Hospital

Des Moines, Iowa, 50316, United States
Iowa Methodist Medical Center

Des Moines, Iowa, 50309, United States
John H Stroger Jr Hospital of Cook County

Chicago, Illinois, 60612, United States
Johns Hopkins University/Sidney Kimmel Cancer Center

Baltimore, Maryland, 21287, United States
Kadlec Clinic Hematology and Oncology

Kennewick, Washington, 99336, United States
Kaiser Permanente - Panorama City

Panorama City, California, 91402, United States
Kaiser Permanente Los Angeles Medical Center

Los Angeles, California, 90027, United States
Kaiser Permanente Washington

Seattle, Washington, 98112, United States
Kaiser Permanente-Anaheim

Anaheim, California, 92806, United States
Kaiser Permanente-Baldwin Park

Baldwin Park, California, 91706, United States
Kaiser Permanente-Bellflower

Bellflower, California, 90706, United States
Kaiser Permanente-Cadillac

Los Angeles, California, 90034, United States
Kaiser Permanente-Fontana

Fontana, California, 92335, United States
Kaiser Permanente-Irvine

Irvine, California, 92618, United States
Kaiser Permanente-Ontario

Ontario, California, 91761, United States
Kaiser Permanente-Riverside

Riverside, California, 92505, United States
Kaiser Permanente-San Diego Mission

San Diego, California, 92108, United States
Kaiser Permanente-San Diego Zion

San Diego, California, 92120, United States
Kaiser Permanente-San Marcos

San Marcos, California, 92078, United States
Kaiser Permanente-Woodland Hills

Woodland Hills, California, 91367, United States
Kalispell Regional Medical Center

Kalispell, Montana, 59901, United States
Katmai Oncology Group

Anchorage, Alaska, 99508, United States
Kettering Medical Center

Kettering, Ohio, 45429, United States
Kootenai Cancer Center

Post Falls, Idaho, 83854, United States
Kootenai Cancer Clinic

Sandpoint, Idaho, 83864, United States
Kootenai Medical Center

Coeur d'Alene, Idaho, 83814, United States
LSU Health Baton Rouge-North Clinic

Baton Rouge, Louisiana, 70805, United States
Lakeview Hospital

Stillwater, Minnesota, 55082, United States
Louisiana Hematology Oncology Associates LLC

Baton Rouge, Louisiana, 70809, United States
Marshfield Clinic

Marshfield, Wisconsin, 54449, United States
Marshfield Clinic - Ladysmith Center

Ladysmith, Wisconsin, 54848, United States
Marshfield Clinic - Weston Center

Weston, Wisconsin, 54476, United States
Marshfield Clinic - Wisconsin Rapids Center

Wisconsin Rapids, Wisconsin, 54494, United States
Marshfield Clinic Cancer Center - Eau Claire

Eau Claire, Wisconsin, 54701, United States
Marshfield Clinic Cancer Center at Sacred Heart

Eau Claire, Wisconsin, 54701, United States
Marshfield Clinic Stevens Point Center

Stevens Point, Wisconsin, 54482, United States
Marshfield Clinic-Chippewa Center

Chippewa Falls, Wisconsin, 54729, United States
Marshfield Clinic-Minocqua Center

Minocqua, Wisconsin, 54548, United States
Marshfield Clinic-Rice Lake Center

Rice Lake, Wisconsin, 54868, United States
Marshfield Clinic-Wausau Center

Wausau, Wisconsin, 54401, United States
Mary Bird Perkins Cancer Center

Baton Rouge, Louisiana, 70809, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States
Medical Oncology Hematology Consultants PA

Newark, Delaware, 19713, United States
Medical Oncology and Hematology Associates-Des Moines

Des Moines, Iowa, 50309, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Memorial Hospital of Carbondale

Carbondale, Illinois, 62902, United States
Memorial Medical Center

Springfield, Illinois, 62781, United States
Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Memorial Sloan Kettering Commack

Commack, New York, 11725, United States
Memorial Sloan Kettering Monmouth

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Rockville Centre

Rockville Centre, New York, 11570, United States
Memorial Sloan Kettering Westchester

Harrison, New York, 10604, United States
Mercy Hospital

Coon Rapids, Minnesota, 55433, United States
Methodist Medical Center of Illinois

Peoria, Illinois, 61636, United States
Methodist West Hospital

West Des Moines, Iowa, 50266-7700, United States
Miami Valley Hospital

Dayton, Ohio, 45409, United States
Miami Valley Hospital North

Dayton, Ohio, 45415, United States
Miami Valley Hospital South

Centerville, Ohio, 45459, United States
Minnesota Oncology Hematology PA-Maplewood

Maplewood, Minnesota, 55109, United States
Minnesota Oncology Hematology PA-Woodbury

Woodbury, Minnesota, 55125, United States
Minor and James Medical PLLC

Seattle, Washington, 98104, United States
Missouri Baptist Medical Center

St Louis, Missouri, 63131, United States
Missouri Baptist Outpatient Center-Sunset Hills

Sunset Hills, Missouri, 63127, United States
Missouri Baptist Sullivan Hospital

Sullivan, Missouri, 63080, United States
Morristown Medical Center

Morristown, New Jersey, 07960, United States
Nanticoke Memorial Hospital

Seaford, Delaware, 19973, United States
Nebraska Methodist Hospital

Omaha, Nebraska, 68114, United States
New Ulm Medical Center

New Ulm, Minnesota, 56073, United States
North Memorial Medical Health Center

Robbinsdale, Minnesota, 55422, United States
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital

Yakima, Washington, 98902, United States
Northshore Oncology Associates-Covington

Covington, Louisiana, 70433, United States
Northwell Health/Center for Advanced Medicine

Lake Success, New York, 11042, United States
OSF Saint Francis Medical Center

Peoria, Illinois, 61637, United States
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center

Pekin, Illinois, 61554, United States
OSF Saint Francis Radiation Oncology at Peoria Cancer Center

Peoria, Illinois, 61615, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Oncology Center of The South Incorporated

Houma, Louisiana, 70360, United States
Oncology Hematology Care Inc - Anderson

Cincinnati, Ohio, 45230, United States
Oncology Hematology Care Inc-Blue Ash

Cincinnati, Ohio, 45242, United States
Oncology Hematology Care Inc-Crestview

Crestview Hills, Kentucky, 41017, United States
Oncology Hematology Care Inc-Eden Park

Cincinnati, Ohio, 45202, United States
Oncology Hematology Care Inc-Healthplex

Fairfield, Ohio, 45014, United States
Oncology Hematology Care Inc-Kenwood

Cincinnati, Ohio, 45236, United States
Oncology Hematology Care Inc-Mercy West

Cincinnati, Ohio, 45211, United States
Orion Cancer Care

Findlay, Ohio, 45840, United States
Our Lady of the Lake Physicians Group - Medical Oncology

Baton Rouge, Louisiana, 70809, United States
Overlook Hospital

Summit, New Jersey, 07902, United States
Pacific Gynecology Specialists

Seattle, Washington, 98104, United States
Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416, United States
Parkland Health Center-Bonne Terre

Bonne Terre, Missouri, 63628, United States
PeaceHealth Saint John Medical Center

Longview, Washington, 98632, United States
PeaceHealth Saint Joseph Medical Center

Bellingham, Washington, 98225, United States
PeaceHealth Southwest Medical Center

Vancouver, Washington, 98664, United States
PeaceHealth United General Medical Center

Sedro-Woolley, Washington, 98284, United States
Penn State Milton S Hershey Medical Center

Hershey, Pennsylvania, 17033-0850, United States
Providence Alaska Medical Center

Anchorage, Alaska, 99508, United States
Providence Newberg Medical Center

Newberg, Oregon, 97132, United States
Providence Oncology and Hematology Care Southeast

Clackamas, Oregon, 97015, United States
Providence Portland Medical Center

Portland, Oregon, 97213, United States
Providence Regional Cancer Partnership

Everett, Washington, 98201, United States
Providence Regional Cancer System-Aberdeen

Aberdeen, Washington, 98520, United States
Providence Regional Cancer System-Centralia

Centralia, Washington, 98531, United States
Providence Regional Cancer System-Lacey

Lacey, Washington, 98503, United States
Providence Regional Cancer System-Shelton

Shelton, Washington, 98584, United States
Providence Regional Cancer System-Yelm

Yelm, Washington, 98597, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center

Burbank, California, 91505, United States
Providence Saint Mary Regional Cancer Center

Walla Walla, Washington, 99362, United States
Providence Saint Vincent Medical Center

Portland, Oregon, 97225, United States
Providence Willamette Falls Medical Center

Oregon City, Oregon, 97045, United States
Radiation Oncology of Northern Illinois

Ottawa, Illinois, 61350, United States
Regional Hematology and Oncology PA

Newark, Delaware, 19713, United States
Regions Hospital

Saint Paul, Minnesota, 55101, United States
Reid Health

Richmond, Indiana, 47374, United States
Rice Memorial Hospital

Willmar, Minnesota, 56201, United States
Ridgeview Medical Center

Waconia, Minnesota, 55387, United States
Rockwood Cancer Treatment Center-DHEC-Downtown

Spokane, Washington, 99204, United States
Rockwood Clinic Cancer Treatment Center-Valley

Spokane Valley, Washington, 99216, United States
Rockwood North Cancer Treatment Center

Spokane, Washington, 99218, United States
Roger Maris Cancer Center

Fargo, North Dakota, 58122, United States
Roswell Park Cancer Institute

Buffalo, New York, 14263, United States
Rush - Copley Medical Center

Aurora, Illinois, 60504, United States
Rush-Copley Healthcare Center

Yorkville, Illinois, 60560, United States
SIH Cancer Institute

Carterville, Illinois, 62918, United States
Saint Charles Health System

Bend, Oregon, 97701, United States
Saint Charles Health System-Redmond

Redmond, Oregon, 97756, United States
Saint Francis Medical Center

Cape Girardeau, Missouri, 63703, United States
Saint Francis Regional Medical Center

Shakopee, Minnesota, 55379, United States
Saint James Community Hospital and Cancer Treatment Center

Butte, Montana, 59701, United States
Saint John's Hospital - Healtheast

Maplewood, Minnesota, 55109, United States
Saint Joseph Medical Center

Bloomington, Illinois, 61701, United States
Saint Luke's Mountain States Tumor Institute

Boise, Idaho, 83712, United States
Saint Luke's Mountain States Tumor Institute - Fruitland

Fruitland, Idaho, 83619, United States
Saint Luke's Mountain States Tumor Institute - Meridian

Meridian, Idaho, 83642, United States
Saint Luke's Mountain States Tumor Institute - Nampa

Nampa, Idaho, 83686, United States
Saint Luke's Mountain States Tumor Institute-Twin Falls

Twin Falls, Idaho, 83301, United States
Saint Patrick Hospital - Community Hospital

Missoula, Montana, 59802, United States
Saint Peter's Community Hospital

Helena, Montana, 59601, United States
Saint Vincent Healthcare

Billings, Montana, 59101, United States
Sainte Genevieve County Memorial Hospital

Sainte Genevieve, Missouri, 63670, United States
Sanford Bismarck Medical Center

Bismarck, North Dakota, 58501, United States
Sanford Broadway Medical Center

Fargo, North Dakota, 58122, United States
Sanford Cancer Center Oncology Clinic

Sioux Falls, South Dakota, 57104, United States
Sanford Joe Lueken Cancer Center

Bemidji, Minnesota, 56601, United States
Sanford USD Medical Center - Sioux Falls

Sioux Falls, South Dakota, 57117-5134, United States
Siteman Cancer Center at Saint Peters Hospital

City of Saint Peters, Missouri, 63376, United States
Siteman Cancer Center at West County Hospital

Creve Coeur, Missouri, 63141, United States
Siteman Cancer Center-South County

St Louis, Missouri, 63129, United States
Smilow Cancer Center/Yale-New Haven Hospital

New Haven, Connecticut, 06510, United States
Smilow Cancer Hospital Care Center-Fairfield

Fairfield, Connecticut, 06824, United States
Smilow Cancer Hospital Care Center-Trumbull

Trumbull, Connecticut, 06611, United States
Southeast Cancer Center

Cape Girardeau, Missouri, 63703, United States
Southern Illinois University School of Medicine

Springfield, Illinois, 62702, United States
Southwest Illinois Health Services LLP

Swansea, Illinois, 62226, United States
Springfield Clinic

Springfield, Illinois, 62702, United States
Springfield Regional Cancer Center

Springfield, Ohio, 45504, United States
Springfield Regional Medical Center

Springfield, Ohio, 45505, United States
Swedish Cancer Institute-Eastside Oncology Hematology

Bellevue, Washington, 98005, United States
Swedish Cancer Institute-Issaquah

Issaquah, Washington, 98029, United States
Swedish Medical Center-Ballard Campus

Seattle, Washington, 98107, United States
Swedish Medical Center-Cherry Hill

Seattle, Washington, 98122-5711, United States
Swedish Medical Center-Edmonds

Edmonds, Washington, 98026, United States
Swedish Medical Center-First Hill

Seattle, Washington, 98122-4307, United States
The Carle Foundation Hospital

Urbana, Illinois, 61801, United States
UPMC Cancer Center at UPMC McKeesport

McKeesport, Pennsylvania, 15132, United States
UPMC Cancer Center at UPMC Northwest

Seneca, Pennsylvania, 16346, United States
UPMC Cancer Centers - Arnold Palmer Pavilion

Greensburg, Pennsylvania, 15601, United States
UPMC Susquehanna

Williamsport, Pennsylvania, 17701, United States
UPMC Uniontown Hospital Radiation Oncology

Uniontown, Pennsylvania, 15401, United States
UPMC Washington Hospital Radiation Oncology

Washington, Pennsylvania, 15301, United States
UPMC-Coraopolis/Heritage Valley Radiation Oncology

Moon Township, Pennsylvania, 15108, United States
UPMC-Heritage Valley Health System Beaver

Beaver, Pennsylvania, 15009, United States
UPMC-Johnstown/John P. Murtha Regional Cancer Center

Johnstown, Pennsylvania, 15901, United States
UPMC-Magee Womens Hospital

Pittsburgh, Pennsylvania, 15213, United States
UPMC-Passavant Hospital

Pittsburgh, Pennsylvania, 15237, United States
UPMC-Presbyterian Hospital

Pittsburgh, Pennsylvania, 15213, United States
UPMC-Saint Clair Hospital Cancer Center

Pittsburgh, Pennsylvania, 15243, United States
UPMC-Saint Margaret

Pittsburgh, Pennsylvania, 15215, United States
UPMC-Shadyside Hospital

Pittsburgh, Pennsylvania, 15232, United States
United Hospital

Saint Paul, Minnesota, 55102, United States
Unity Hospital

Fridley, Minnesota, 55432, United States
University of Colorado Hospital

Aurora, Colorado, 80045, United States
University of Iowa/Holden Comprehensive Cancer Center

Iowa City, Iowa, 52242, United States
University of Michigan Comprehensive Cancer Center

Ann Arbor, Michigan, 48109, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Pittsburgh Cancer Institute (UPCI)

Pittsburgh, Pennsylvania, 15232, United States
Upper Valley Medical Center

Troy, Ohio, 45373, United States
Valley Radiation Oncology

Peru, Illinois, 61354, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Wayne Hospital

Greenville, Ohio, 45331, United States
Welch Cancer Center

Sheridan, Wyoming, 82801, United States
Western Illinois Cancer Treatment Center

Galesburg, Illinois, 61401, United States
Woodland Cancer Care Center

Michigan City, Indiana, 46360, United States
Yale University

New Haven, Connecticut, 06520, United States

Conditions

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SALIVARY CANCER