New hope for recurrent prostate cancer: drug combo aims to delay PSA rise without hormones

NCT ID NCT06096870

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 30 times

Summary

This study tests whether adding an injected drug (PDS01ADC) to a daily pill (enzalutamide) can better control prostate cancer that has returned after initial treatment. About 65 men with rising PSA and positive PET scans will be enrolled. The goal is to see if the combination keeps PSA levels low longer than enzalutamide alone, without using standard hormone therapy.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

Conditions

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