New hope for prostate cancer: enzalutamide slows progression in asian men

NCT ID NCT02294461

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 study tested the drug enzalutamide in 395 Asian men with metastatic prostate cancer that had stopped responding to standard hormone therapy. Participants had not yet received chemotherapy. The study compared enzalutamide to a placebo to see if it could delay rises in PSA levels, a marker of cancer progression. The goal was to assess whether enzalutamide could help control the disease for a longer time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

enzalutamide (Xtandi)

What this could lead to

If successful, enzalutamide could offer a new treatment option to delay cancer progression in men with metastatic prostate cancer who have not yet had chemotherapy.

What could go wrong

This trial is completed, but results may not apply to all populations. Enzalutamide can cause side effects like fatigue, high blood pressure, and falls. It controls the disease, not cures it.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

castration-resistant prostate carcinoma Kennedy disease metastatic prostate carcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CN00102

    Shanghai, China

  • CN00103

    Beijing, China

  • CN00104

    Beijing, China

  • CN00105

    Shanghai, China

  • CN00106

    Beijing, China

  • CN00107

    Hangzhou, China

  • CN00108

    Shanghai, China

  • CN00109

    Wuhan, China

  • CN00110

    Nanjing, China

  • CN00111

    Beijing, China

  • CN00112

    Beijing, China

  • CN00113

    Shanghai, China

  • CN00114

    Beijing, China

  • CN00115

    Beijing, China

  • CN00117

    Nanjing, China

  • CN00118

    Wenzhou, China

  • CN00119

    Suzhou, China

  • CN00121

    Changsha, China

  • CN00124

    Xi'an, China

  • CN00125

    Tianjin, China

  • CN00126

    Shanghai, China

  • CN00127

    Beijing, China

  • HK00402

    Hong Kong, Hong Kong

  • KR00201

    Incheon, South Korea

  • KR00202

    Seongnam-si, South Korea

  • KR00203

    Daegu, South Korea

  • KR00204

    Seoul, South Korea

  • KR00205

    Busan, South Korea

  • KR00206

    Seoul, South Korea

  • KR00207

    Busan, South Korea

  • KR00208

    Seoul, South Korea

  • KR00209

    Seoul, South Korea

  • KR00210

    Seoul, South Korea

  • KR00211

    Seoul, South Korea

  • KR00212

    Cheongju-si, South Korea

  • KR00213

    Daejeon, South Korea

  • KR00214

    Anyang, South Korea

  • KR00215

    Seoul, South Korea

  • TW00301

    Taipei, Taiwan

  • TW00302

    Taichung, Taiwan

  • TW00303

    Taichung, Taiwan

  • TW00304

    Taipei, Taiwan

  • TW00305

    Taoyuan County, Taiwan

  • TW00306

    Taipei, Taiwan

  • TW00307

    Tainan, Taiwan

  • TW00308

    Tainan, Taiwan

  • TW00309

    Kaohsiung City, Taiwan