New drug combo shows promise for chinese men with advanced prostate cancer

NCT ID NCT04076059

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 study tested whether adding enzalutamide (Xtandi) to standard hormone therapy (ADT) helps Chinese men with metastatic hormone-sensitive prostate cancer. 180 participants received either enzalutamide plus ADT or a placebo plus ADT. The main goal was to see how long it took for PSA levels to rise, a sign of cancer progression.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

enzalutamide (Xtandi)

What this could lead to

If successful, this combination could become a new standard treatment for Chinese men with metastatic hormone-sensitive prostate cancer, delaying disease progression.

What could go wrong

This is a phase 3 trial, but results may not apply to all populations. Side effects of enzalutamide include fatigue, hot flashes, and high blood pressure. The study is complete but not yet published.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metastatic prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Site CN86001

    Guangzhou, China

  • Site CN86002

    Shanghai, China

  • Site CN86003

    Shanghai, China

  • Site CN86004

    Nanchang, China

  • Site CN86005

    Ürümqi, China

  • Site CN86009

    Changsha, China

  • Site CN86010

    Shanghai, China

  • Site CN86011

    Shenzhen, China

  • Site CN86012

    Tianjin, China

  • Site CN86013

    Shanghai, China

  • Site CN86014

    Shanghai, China

  • Site CN86016

    Changsha, China

  • Site CN86017

    Zhengzhou, China

  • Site CN86019

    Wuhan, China

  • Site CN86020

    Shenyang, China

  • Site CN86021

    Wuxi, China

  • Site CN86022

    Beijing, China

  • Site CN86023

    Changsha, China

  • Site CN86024

    Changchun, China

  • Site CN86025

    Fuzhou, China

  • Site CN86026

    Wuhan, China

  • Site CN86027

    Shanghai, China

  • Site CN86028

    Hangzhou, China

  • Site CN86029

    Zhengzhou, China

  • Site CN86032

    Suzhou, China

  • Site CN86035

    Beijing, China

  • Site CN86036

    Hangzhou, China

  • Site CN86038

    Xi'an, China