New dosing method could reduce organ damage in sickle cell patients

NCT ID NCT07177300

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 30 times

Summary

This study aims to improve how hydroxyurea is dosed for people with sickle cell anemia. Instead of using only weight, the new method considers how each person absorbs the drug. Researchers hope this will reduce damage to the brain, kidneys, heart, and spleen. The study enrolls 50 children and adults starting hydroxyurea therapy.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

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