Supercharged immune cells target Hard-to-Treat cancers

NCT ID NCT03967223

Summary

This study tests whether genetically modified immune cells can safely shrink tumors in people with advanced synovial sarcoma or liposarcoma. Researchers collect patients' own T-cells, engineer them to recognize cancer proteins, then infuse them back into the body. The trial is for patients whose tumors test positive for specific markers and who meet other health criteria.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU de Bordeaux GH Sud Hôpital Haut Lévêque

    Pessac, 33604, France

  • CIUSSS de L'Est-De-Lile-De-Montreal

    Montreal, Quebec, H1T 2M4, Canada

  • Centre Léon Bérard

    Lyon, 69373, France

  • Christie Hospital NHS Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02114, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Fondazione IRCCS Instituto Nazionale Dei Tumori

    Milan, Lombardy, 20133, Italy

  • Fred Hutchinson Cancer Research

    Seattle, Washington, 98109-1024, United States

  • Froedtert Hospital

    Milwaukee, Wisconsin, 53226, United States

  • Hospital Santa Creu Y Sant Pau

    Barcelona, 08025, Spain

  • Hospital Universitario Fundación Jiménez Díaz

    Madrid, 28040, Spain

  • Hospital Virgen Del Rocio

    Seville, 41013, Spain

  • Ico Duran y Reynals l'Hospitalet de Llobrega

    Hospitalet de Llobregat, Barcelona, 08907, Spain

  • Ircss Istituto Clinico Humanitas

    Rozzano (MI), Lombardy, 20089, Italy

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic Jacksonville

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic Rochester

    Rochester, Minnesota, 55905, United States

  • Memorial Sloan Kettering cancer center

    New York, New York, 10065, United States

  • Minnesota Oncology Hematology

    Minneapolis, Minnesota, 55455, United States

  • Ohio State University-Columbus

    Columbus, Ohio, 43210, United States

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2M9, Canada

  • Royal Marsden Hospital

    London, SW3 6JJ, United Kingdom

  • Sarah Cannon Research Institute

    Denver, Colorado, 80218, United States

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • Stanford Hospital and Clinics

    Stanford, California, 94305, United States

  • The Netherlands Cancer Institute

    Amsterdam, 1066 CX, Netherlands

  • University College Hospital-London

    London, WC1E 6AG, United Kingdom

  • University Of Texas Southwestern Medical Center

    Dallas, Texas, 75390-8565, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of Iowa College of Medicine

    Iowa City, Iowa, 52242-1009, United States

  • University of Michigan Medical Center

    Ann Arbor, Michigan, 48109, United States

  • University of Pittsburgh, Hillman Cancer Centre

    Pittsburgh, Pennsylvania, 15232, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390-9063, United States

  • University of Utah

    Salt Lake City, Utah, 84112, United States

  • Virginia Commonwealth University

    Richmond, Virginia, 23298, United States

  • Washington University

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.