New ALS drug tested for safety in small trial
NCT ID NCT04632225
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested the safety of an experimental drug called engensis in 18 people with amyotrophic lateral sclerosis (ALS). Participants received either engensis or a placebo injection into their muscles. The main goal was to check for side effects, while also exploring effects on muscle strength, breathing, and quality of life. The study did not aim to cure ALS, but to see if the drug is safe enough for further testing.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Austin Neuromuscular Center
Austin, Texas, 78759, United States
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Hanyang University Medical Center
Seoul, 04763, South Korea
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Johns Hopkins University Department of Neurology
Baltimore, Maryland, 21205, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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St. Joseph's Hospital and Medical Center, Barrows Neurological Institute
Phoenix, Arizona, 85013, United States