New drug combo tested in fight against advanced bladder cancer

NCT ID NCT03288545

Ongoing Disease control Sponsor: Astellas Pharma Global Development, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing an experimental drug called enfortumab vedotin, both by itself and combined with other cancer therapies, for people with advanced bladder and urinary tract cancers. It aims to find safe doses and see if these treatments can shrink tumors. The study includes about 348 people whose cancer has spread or is at a high risk of spreading.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Alaska Urological Institute

Anchorage, Alaska, 99503, United States
Allegheny General Hospital

Pittsburgh, Pennsylvania, 15212, United States
Arizona Oncology Associates, PC - HOPE

Tucson, Arizona, 85710, United States
Banner MD Anderson Cancer Center

Gilbert, Arizona, 85234, United States
Boca Raton Regional Hospital / Lynn Cancer Institute

Boca Raton, Florida, 33486, United States
CMOH Broomall

Broomall, Pennsylvania, 19008, United States
Cardinal Bernardin Cancer Center / Loyola University Medical Center

Maywood, Illinois, 60153, United States
Carolina Urologic Research Center

Myrtle Beach, South Carolina, 29572, United States
Case Western Reserve University / University Hospitals Case Medical Center

Cleveland, Ohio, 44106, United States
Decatur Memorial Hospital - Illinois

Decatur, Illinois, 62526, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
Eastern CT Hematology and Oncology Associates

Norwich, Connecticut, 06360, United States
Fox Chase Cancer Center

Philadelphia, Pennsylvania, 19111, United States
Gabrail Cancer Center Research, LLC

Canton, Ohio, 44718, United States
Georgetown University Medical Center

Washington D.C., District of Columbia, 20007, United States
Hackensack University Medical Center

Hackensack, New Jersey, 07601, United States
Henry Ford Health System

Detroit, Michigan, 48202, United States
Highlands Oncology Group

Fayetteville, Arkansas, 72703, United States
Holy Cross Hospital - Michael and Dianne Bienes Comprehensive Cancer Center

Fort Lauderdale, Florida, 33308, United States
Kaiser Permanente Southern California

Woodland Hills, California, 91367, United States
Levine Cancer Institute

Charlotte, North Carolina, 28204, United States
Maryland Oncology Hematology, P.A.

Silver Spring, Maryland, 20904, United States
Mayo Clinic Arizona

Phoenix, Arizona, 85054, United States
Mayo Clinic Florida

Jacksonville, Florida, 32224, United States
McLaren Greater Lansing Hospital

Lansing, Michigan, 48910, United States
Medical College of Wisconsin (Milwaukee)

Milwaukee, Wisconsin, 53226, United States
Medical Oncology Associates

Spokane, Washington, 99208, United States
Medical University of South Carolina/Hollings Cancer Center

Charleston, South Carolina, 29425, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10087-9049, United States
Memorial Sloan Kettering Cancer Center - Basking Ridge

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Cancer Center - Bergen

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center - Commack

Commack, New York, 11725, United States
Memorial Sloan Kettering Cancer Center - Monmouth

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Cancer Center - Nassau

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Cancer Center - Westchester

Harrison, New York, 10604, United States
NYU Winthrop Hospital

Mineola, New York, 11501, United States
Nebraska Hematology Oncology P.C.

Lincoln, Nebraska, 68506, United States
New York Oncology Hematology, P.C.

Albany, New York, 12206, United States
New York University (NYU) Cancer Institute

New York, New York, 10016, United States
Northwell Cancer Center / Monter Cancer Center

Lake Success, New York, 11042, United States
Northwestern Medicine Cancer Center - Kishwaukee / Kishwaukee Cancer Center

DeKalb, Illinois, 60115, United States
Northwestern Medicine Cancer Center - Warrenville / Central DuPage Hospital - Cancer Care

Warrenville, Illinois, 60555, United States
Northwestern Medicine Cancer Center Delnor

Geneva, Illinois, 60134, United States
Ochsner Clinic Foundation

New Orleans, Louisiana, 70121, United States
OptumCare Cancer Center

Las Vegas, Nevada, 89102, United States
Penn State Milton S. Hershey Medical Center

Hershey, Pennsylvania, 17033, United States
Piedmont Cancer Institute

Atlanta, Georgia, 30309, United States
Rocky Mountain Cancer Centers - Aurora

Aurora, Colorado, 80012, United States
Roswell Park Cancer Institute

Buffalo, New York, 14263, United States
Saint Francis Hospital Cancer Center

Greenville, South Carolina, 29607, United States
Saint Joseph Heritage Medical Group

Santa Rosa, California, 95403, United States
Sarah Cannon Research Institute

Chattanooga, Tennessee, 37404, United States
Site CA11001

Toronto, Ontario, M5G 2M9, Canada
Site CA11002

Sherbrooke, Quebec, J1H 5N4, Canada
Site CA11005

Montreal, Quebec, H3T1E2, Canada
Site CA11008

East Brampton, Ontario, L6R 3J7, Canada
Site CA11011

Kingston, Ontario, K7L 2V7, Canada
Site CA11013

Montreal, Quebec, H4A3J1, Canada
Site ES34001

Madrid, 28034, Spain
Site ES34004

Santander, 39008, Spain
Site ES34005

Sabadell, 08208, Spain
Site ES34006

Barcelona, 08041, Spain
Site ES34007

Pamplona, 31008, Spain
Site ES34008

Madrid, 28033, Spain
Site ES34012

Madrid, 28041, Spain
Site FR33001

Strasbourg, 67200, France
Site FR33002

Nice, 06189, France
Site FR33003

Lyon, 69008, France
Site FR33004

Marseille, 13273, France
Site FR33005

Dijon, 21000, France
Site FR33006

Pierre-Bénite, 69310, France
Site FR33008

Bordeaux, 33000, France
Site FR33010

Moselle, 54519, France
Site IT39002

Terni, 05100, Italy
Site PR78701

Rio Piedras, 00935, Puerto Rico
Southcoast Centers for Cancer Care - Fairhaven Site

Fairhaven, Massachusetts, 02719, United States
Stanford Cancer Center / Blood & Marrow Transplant Program

Stanford, California, 94305, United States
Tennessee Oncology / Sarah Cannon Research Institute

Nashville, Tennessee, 37203, United States
Texas Oncology - Fort Worth Cancer Center

Fort Worth, Texas, 76104, United States
Texas Oncology - Tyler

Tyler, Texas, 75702, United States
Toledo Clinic Cancer Center

Toledo, Ohio, 43623, United States
Tower Hematology Oncology Medical Group

Beverly Hills, California, 90211, United States
Tulane University Hospital and Clinic

New Orleans, Louisiana, 70112, United States
UC San Diego / Moores Cancer Center

La Jolla, California, 92093, United States
UNC Lineberger Comprehensive Cancer Center / University of North Carolina

Chapel Hill, North Carolina, 27599, United States
University of California Irvine - Newport

Orange, California, 92868, United States
University of California at San Francisco

San Francisco, California, 94134, United States
University of California, Davis Comprehensive Cancer Center

Sacramento, California, 95817, United States
University of Chicago Medical Center

Chicago, Illinois, 60637-1470, United States
University of Colorado Hospital / University of Colorado

Aurora, Colorado, 80045-0510, United States
University of Kansas Cancer Center

Westwood, Kansas, 66205, United States
University of Miami

Miami, Florida, 33136, United States
University of Michigan Comprehensive Cancer Center

Ann Arbor, Michigan, 48109, United States
University of Minnesota

Minneapolis, Minnesota, 55455, United States
University of Mississippi Medical Center

Jackson, Mississippi, 39213, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106, United States
University of Rochester Medical Center

Rochester, New York, 14642, United States
University of Texas Health Science Center at San Antonio

San Antonio, Texas, 78229, United States
University of Virginia

Charlottesville, Virginia, 22903, United States
Utah Cancer Specialists

Salt Lake City, Utah, 84106, United States
Vidant Medical Center

Greenville, North Carolina, 27834, United States
Virginia Oncology Associates - Norfolk

Norfolk, Virginia, 23502, United States
Washington University School of Medicine - Siteman Cancer Center

St Louis, Missouri, 63110, United States
Weill Cornell Medical College

New York, New York, 10065, United States
Winship Cancer Institute / Emory University School of Medicine

Atlanta, Georgia, 30322, United States
Yale Cancer Center

New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.

CARCINOMA, TRANSITIONAL CELL RENAL PELVIS NEOPLASMS URETERAL NEOPLASMS URETHRAL NEOPLASMS URINARY BLADDER NEOPLASMS UROLOGIC NEOPLASMS UROTHELIAL CANCER