New hope for stubborn high blood pressure: drug targets hidden vessel damage

NCT ID NCT04388124

First seen Mar 06, 2026 · Last updated May 16, 2026 · Updated 11 times

Summary

This study tests whether a drug that blocks endothelin-1 can improve blood vessel function and lower blood pressure in people with resistant hypertension (high blood pressure that doesn't respond to standard treatments). About 24 adults aged 30-80 will take the drug for 8 weeks. The goal is to see if it helps blood vessels work better and is safe for the kidneys.

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Contacts and locations

Locations

  • Chu Rouen

    RECRUITING

    Rouen, 76031, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.