A new test may spot which women need pain care before endometriosis surgery
NCT ID NCT06997809
First seen Sep 04, 2026 · Last updated Sep 04, 2026
Summary
This trial tests whether screening women with endometriosis for pain complications before surgery, and offering specialized pain care to those who need it, improves their quality of life a year after the operation. Researchers will compare women who receive this extra pain management pathway with those who get standard surgical care alone. The study includes women aged 18 to 50 with confirmed endometriosis and pain that affects their daily life, who are scheduled for surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- A care pathway that adds a specialized pain consultation before endometriosis surgery, with tailored pain treatment if screening tests are positive.
- What this could lead to
- If it works, this could show that screening for pain complications before surgery and treating them improves quality of life after endometriosis surgery.
- What could go wrong
- The trial is relatively small and early, and the benefit may not be clear. The added consultation could delay surgery or not help all women.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 187 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2026
- Expected to finish
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Dec 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: * Maternal age from 18 up to 50 years old (50 non included). * Women affiliated to social coverage insurance * Women who understand French * Women who signed the written consent * Women with impaired quality of life (pain) linked to endometriosis * Women with formal radiological signs of endometriosis (MRI lesions more than 5 mm or endometrioma more than 20 mm on radiological examinations). * Surgical indication for resection of lesions by laparoscopy or robotic surgery for management of pain or impairment of quality of life * Patients requiring complete conservative or radical resections of all lesions * Indication of surgery validated within dedicated meeting for endometriosis. * Purpose of pain associated or not with infertility * Date of surgery fixed with sufficient time for algological treatment. Maximum delay of 4 months between randomization and surgery Exclusion criteria: * Women undergoing surgery for the purpose of infertility * Patient with previous surgery for removal of deep lesions of endometriosis or endometriotic cysts (history of exploratory laparoscopy accepted) * Patient with suspicious lesions on MRI or specialized ultrasound. * A patient who needs to be treated for another uterine pathology at the same time. * Pregnant women * Patient with a desire for pregnancy immediately and/or within one year after surgery * Women who refuse clinical examination (some algological tests couldn't be performed without clinical examination) * Patient who has already received algological treatment or who should receive it before surgery * Patient with previous other psychiatric disorders (depressive symptoms treated) * Women without rights
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
9 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Bordeaux University Hospital
NOT_YET_RECRUITINGBordeaux, France, 33000, France
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IFEMENDO
NOT_YET_RECRUITINGBordeaux, France, 33000, France
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Limoges University hospital
RECRUITINGLimoges, France, 87042, France
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Mutual Clinic La Sagesse
NOT_YET_RECRUITINGRennes, France, 33043, France
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Poissy-St-Germain Intercommunal hospital center
NOT_YET_RECRUITINGPoissy, France, 78303, France
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Poitiers University Hospital
NOT_YET_RECRUITINGPoitiers, France, 86000, France
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Saint-Vincent-de-Paul Hospital
NOT_YET_RECRUITINGLille, France, 59000, France
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South Hospital Rennes University Hospital
NOT_YET_RECRUITINGRennes, France, 35203, France
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Versailles Hospital
NOT_YET_RECRUITINGLe Chesnay, France, 78150, France
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