New drug combo tested for Tough-to-Treat uterine cancer

NCT ID NCT04463771

Ongoing Disease control Sponsor: Incyte Corporation Source: ClinicalTrials.gov ↗

Summary

This study is testing an immunotherapy drug called retifanlimab, given alone or with other drugs, for women with advanced endometrial (uterine) cancer that has continued to grow despite standard platinum-based chemotherapy. The main goal is to see if the treatment can shrink tumors and control the cancer. It involves about 206 participants and is designed to match different drug combinations to specific genetic features of each person's tumor.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Advent Health Medical Group-Orlando 2501

Orlando, Florida, 32804, United States
Alaska Womens Cancer Care Akwcc

Anchorage, Alaska, 99508, United States
Alexandra General Hospital of Athens

Athens, 11528, Greece
Arizona Oncology Associates

Tucson, Arizona, 85711, United States
Azienda Ospedaliero-Universitaria Di Bologna Policlinico S. Orsola - Malpighi

Bologna, 40138, Italy
Barbara Ann Karmanos Cancer Hospital

Detroit, Michigan, 48201, United States
Billings Clinic Cancer Center

Billings, Montana, 59101, United States
Broward Health Medical Center

Fort Lauderdale, Florida, 33316, United States
Cario - Centre Armoricain de Radiotherapie Imagerie Medicale Et Oncologie

Plérin, 22190, France
Caucasus Medical Centre Llc

Tbilisi, 00186, Georgia
Centre Hospitalier Universitaire de Liege - Sart Tilman

Liège, 04000, Belgium
Centre de Lutte Contre Le Cancer - Institut de Cancerologie de L'Ouest - Rene Gauducheau

Saint-Herblain, 44800, France
Charite - Campus Virchow-Klinikum

Berlin, 13353, Germany
Chu Besancon Hospital Jean Minjoz

Besançon, 25000, France
Chu Ucl Namur de Saint Elisabeth

Namur, 05000, Belgium
Comitato Etico Fondazione Irccs Istituto Nazionale Dei Tumori Milano

Milan, 20133, Italy
Comprehensive Cancer Centers of Nevada

Henderson, Nevada, 89074, United States
Euromedica General Clinic of Thessaloniki

Thessaloniki, 54645, Greece
European Institute of Oncology

Milan, 20141, Italy
Fondazione Policlinico Universitario Agostino Gemelli Irccs

Roma, 00168, Italy
Georgia Cancer Center

Augusta, Georgia, 30912, United States
Ghent University Hospital

Ghent, 09000, Belgium
H. Lee Moffitt Cancer Center and Research Institute Hospital

Tampa, Florida, 33612-9497, United States
High Technology Hospital Medcenter

Batumi, 06000, Georgia
Honorhealth

Phoenix, Arizona, 85016, United States
Hospital Cochin Cancerologie

Paris, 75006, France
Hygeia Hospital

Marousi, 15123, Greece
INNOVA

Tbilisi, 00186, Georgia
Institut Bergonie

Bordeaux, 33076, France
Institut Gustave Roussy

Villejuif, 94805, France
Institut Jules Bordet

Brussels, 01000, Belgium
Iov - Istituto Oncologico Veneto Irccs

Padua, 35128, Italy
Istituto Di Ricovero E Cura A Carattere Scientifico (Irccs) Ospedale San Raffaele

Milan, 20132, Italy
Istituto Nazionale Tumori Irccs Fondazione Pascale

Naples, 80131, Italy
Istituto Scientifico Romagnolo Per Lo Studio E La Cura Dei Tumori

Meldola, 47014, Italy
Jsc Evex Hospitals

Kutaisi, 04600, Georgia
Klinikum Kassel Gmbh

Kassel, 34125, Germany
Laura & Isaac Perlmutter Cancer Ctr

New York, New York, 10016, United States
Miami Cancer Institute

Miami, Florida, 33176, United States
Midwest Cancer Care

Kansas City, Missouri, 64132, United States
Minnesota Oncology-Maplewood

Coon Rapids, Minnesota, 55433, United States
Mount Sinai Medical Center Comprehensive Cancer Center

Miami Beach, Florida, 33140, United States
Multiprofile Clinic Consilium Medulla Llc

Tbilisi, 00186, Georgia
New Mexico Cancer Care Alliance

Albuquerque, New Mexico, 87131, United States
O.L.V Ziekenhuis

Aalst, 09300, Belgium
Olive View Med Ctr

Sylmar, California, 91342, United States
Ospedale Santa Maria Ca Foncello

Treviso, 31100, Italy
Presidio Ospedaliero Di Summa Antonio Perrino

Brindisi, 72100, Italy
Tennessee Oncology

Nashville, Tennessee, 37203, United States
Texas Oncology San Antonio

San Antonio, Texas, 78240, United States
Texas Oncology the Woodlands

Shenandoah, Texas, 77380, United States
Texas Oncology-Austin Center

Austin, Texas, 78731, United States
Texas Oncology-Fort Worth South Henderson

Fort Worth, Texas, 76104-3902, United States
Texas Oncology-Tyler

Sioux Falls, South Dakota, 57104, United States
The Ohio State University Wexner Medical Center Division of Gynecologic Oncology

Hilliard, Ohio, 43026, United States
Todua Clinic, Llc

Tbilisi, 00112, Georgia
UCLA Medical Hematology & Oncology

Los Angeles, California, 90048, United States
Universitaire Ziekenhuis Leuven - Gasthuisberg

Leuven, 03000, Belgium
Universitarsfrauenklinik Ulm

Ulm, 89075, Germany
University Clinic Carl Gustav Carus Technical University Dresden

Dresden, 01307, Germany
University Hospital of West Attica - Attikon

Athens, 12462, Greece
University of North Carolina At Chapel Hill

Chapel Hill, North Carolina, 27514, United States
Virginia Commonwealth University

Richmond, Virginia, 23298, United States
Washington University

St Louis, Missouri, 63110, United States
Willamette Valley Cancer Institute

Eugene, Oregon, 97401-8122, United States

Conditions

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ENDOMETRIAL CANCER