New drug combo tested for Tough-to-Treat uterine cancer

NCT ID NCT02755844

Summary

This study tested the safety and effectiveness of a combination of three existing drugs—olaparib, cyclophosphamide, and metformin—for women with recurrent or advanced endometrial (uterine) cancer that had stopped responding to standard chemotherapy. The main goals were to find the safest dose and see if the combination could stop the cancer from growing. The trial involved 35 participants and was an early-stage study to gather initial evidence.

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Contacts and locations

Locations

  • Centre Hospitalier Lyon Sud

    Pierre-Bénite, 69495, France

  • Comité Gynécologique, Institut Gustave Roussy

    Villejuif, 94800, France

  • Département d'Oncologie Médicale, Centre Antoine Lacassagne

    Nice, 06189, France

  • Département de Cancérologie Cervico-Faciale et Thoracique, Centre Oscar Lambret

    Lille, 59000, France

  • Service d'Oncologie Médicale, Centre François Baclesse

    Caen, 14076, France

  • Service d'Oncologie Médicale, Institut Curie

    Paris, 75248, France

Conditions

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