Major trial tests drug combo to fight advanced uterine cancer

NCT ID NCT03981796

Ongoing Disease control Sponsor: Tesaro, Inc. Source: ClinicalTrials.gov ↗

Summary

This large Phase 3 study is testing whether adding the immunotherapy drug dostarlimab to standard chemotherapy helps women with advanced or recurrent endometrial cancer live longer and keeps their cancer from progressing. The trial involves 785 participants who are randomly assigned to receive either the new combination or standard chemotherapy plus a placebo. Researchers are comparing survival, time until the cancer worsens, and quality of life between the two groups.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

GSK Investigational Site

Phoenix, Arizona, 85016, United States
GSK Investigational Site

Scottsdale, Arizona, 85016, United States
GSK Investigational Site

Tucson, Arizona, 85704, United States
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Tucson, Arizona, 85710, United States
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Newport Beach, California, 92663, United States
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Palo Alto, California, 94304, United States
GSK Investigational Site

Deerfield Beach, Florida, 33442, United States
GSK Investigational Site

Jacksonville, Florida, 32207, United States
GSK Investigational Site

Miami, Florida, 33136, United States
GSK Investigational Site

Miami, Florida, 33176, United States
GSK Investigational Site

Orlando, Florida, 32804, United States
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Atlanta, Georgia, 30342, United States
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Augusta, Georgia, 30912, United States
GSK Investigational Site

Savannah, Georgia, 31405, United States
GSK Investigational Site

Hinsdale, Illinois, 60521, United States
GSK Investigational Site

Zion, Illinois, 60099, United States
GSK Investigational Site

Fort Wayne, Indiana, 46845, United States
GSK Investigational Site

Indianapolis, Indiana, 46202, United States
GSK Investigational Site

Indianapolis, Indiana, 46260, United States
GSK Investigational Site

Iowa City, Iowa, 52242, United States
GSK Investigational Site

Lexington, Kentucky, 40536, United States
GSK Investigational Site

Covington, Louisiana, 70433, United States
GSK Investigational Site

New Orleans, Louisiana, 70121, United States
GSK Investigational Site

Shreveport, Louisiana, 71103, United States
GSK Investigational Site

Boston, Massachusetts, 02114, United States
GSK Investigational Site

Springfield, Massachusetts, 01199, United States
GSK Investigational Site

Detroit, Michigan, 48201, United States
GSK Investigational Site

St Louis, Missouri, 63108, United States
GSK Investigational Site

Lebanon, New Hampshire, 03756, United States
GSK Investigational Site

Albuquerque, New Mexico, 87131, United States
GSK Investigational Site

Rio Rancho, New Mexico, 87124, United States
GSK Investigational Site

Albany, New York, 12208, United States
GSK Investigational Site

Mineola, New York, 10016, United States
GSK Investigational Site

New York, New York, 10016, United States
GSK Investigational Site

The Bronx, New York, 10461, United States
GSK Investigational Site

Charlotte, North Carolina, 28204, United States
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Durham, North Carolina, 27710, United States
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Kernersville, North Carolina, 27284, United States
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Mount Airy, North Carolina, 27030, United States
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Winston-Salem, North Carolina, 27103, United States
GSK Investigational Site

Cincinnati, Ohio, 45219, United States
GSK Investigational Site

Cincinnati, Ohio, 45220, United States
GSK Investigational Site

Cleveland, Ohio, 44106, United States
GSK Investigational Site

Columbus, Ohio, 43210, United States
GSK Investigational Site

Hilliard, Ohio, 43026, United States
GSK Investigational Site

Hilliard, Ohio, 43210, United States
GSK Investigational Site

Tulsa, Oklahoma, 74146, United States
GSK Investigational Site

Philadelphia, Pennsylvania, 19111, United States
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Pittsburgh, Pennsylvania, 15224, United States
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Willow Grove, Pennsylvania, 19090, United States
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Providence, Rhode Island, 02905, United States
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Knoxville, Tennessee, 37920, United States
GSK Investigational Site

Austin, Texas, 78731, United States
GSK Investigational Site

Austin, Texas, 78758, United States
GSK Investigational Site

Dallas, Texas, 75246, United States
GSK Investigational Site

Dallas, Texas, 76104, United States
GSK Investigational Site

Charlottesville, Virginia, 22903, United States
GSK Investigational Site

Roanoke, Virginia, 24016, United States
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Seattle, Washington, 98109, United States
GSK Investigational Site

Grodno, 230030, Belarus
GSK Investigational Site

Minsk, 223040, Belarus
GSK Investigational Site

Aalst, 9300, Belgium
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Leuven, 3000, Belgium
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Liège, 4000, Belgium
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Calgary, Alberta, T2N 5G2, Canada
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Winnipeg, Manitoba, R3E 0V9, Canada
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Ottawa, Ontario, K1H 8L6, Canada
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Sault Ste. Marie, Ontario, P6B 0A8, Canada
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Toronto, Ontario, M5G 2M9, Canada
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Montreal, Quebec, H2X 3E4, Canada
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Montreal, Quebec, H4A 3J1, Canada
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Québec, Quebec, G1J 1Z4, Canada
GSK Investigational Site

Brno, 625 00, Czechia
GSK Investigational Site

Prague, 128 51, Czechia
GSK Investigational Site

Aalborg, 9000, Denmark
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Copenhagen, DK-2100, Denmark
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Herlev, 2730, Denmark
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Odense C, 5000, Denmark
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Roskilde, 4000, Denmark
GSK Investigational Site

Kuopio, 70210, Finland
GSK Investigational Site

Tampere, 33520, Finland
GSK Investigational Site

Turku, 20520, Finland
GSK Investigational Site

Amberg, 92224, Germany
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Bad Homburg, 61352, Germany
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Cologne, 50935, Germany
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Dessau, 06847, Germany
GSK Investigational Site

Dresden, 01307, Germany
GSK Investigational Site

Essen, 45136, Germany
GSK Investigational Site

Essen, 45147, Germany
GSK Investigational Site

Frankfurt, 20259, Germany
GSK Investigational Site

Giessen, 35392, Germany
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Hamburg, 20246, Germany
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Hanover, 30177, Germany
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Jena, 07747, Germany
GSK Investigational Site

Karlsruhe, 76135, Germany
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Kiel, 24105, Germany
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Lübeck, 23538, Germany
GSK Investigational Site

Mainz, 55131, Germany
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München, 81675, Germany
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Offenbach, 63069, Germany
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Ravensburg, 88212, Germany
GSK Investigational Site

Rosenheim, 83022, Germany
GSK Investigational Site

Tübingen, 72076, Germany
GSK Investigational Site

Ulm, 89075, Germany
GSK Investigational Site

Wiesbaden, 65189, Germany
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Marousi, 151 23, Greece
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Thessaloniki, 54645, Greece
GSK Investigational Site

Budapest, 1122, Hungary
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Debrecen, 4032, Hungary
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Ashkelon, 78278, Israel
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Beersheba, 8410101, Israel
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Haifa, 3436212, Israel
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Jerusalem, 9112001, Israel
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Petah Tikva, 4941492, Israel
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Rehovot, 7661041, Israel
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Tel Aviv, 6423906, Israel
GSK Investigational Site

Candiolo, 10060, Italy
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Carpi MO, 41012, Italy
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Lecce, 73100, Italy
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Milan, 20133, Italy
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Naples, 00144, Italy
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Ponderano BI, 13875, Italy
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Rome, 00128, Italy
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Sassuolo, 41049, Italy
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Trento, 38122, Italy
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Udine, 33100, Italy
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Amsterdam, 1105 AZ, Netherlands
GSK Investigational Site

Eindhoven, 5623 EJ, Netherlands
GSK Investigational Site

Enschede, 7512 KZ, Netherlands
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Groningen, 9713 GZ, Netherlands
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Maastricht, 6229 HX, Netherlands
GSK Investigational Site

Rotterdam, 3015 GD, Netherlands
GSK Investigational Site

Bergen, 5053, Norway
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Oslo, 0379, Norway
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Stavanger, 4011, Norway
GSK Investigational Site

Troms, 9019, Norway
GSK Investigational Site

Trondheim, 7006, Norway
GSK Investigational Site

Bialystok, 15-027, Poland
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Gdynia, 81-519, Poland
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Lodz, 93-513, Poland
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Olsztyn, 10-228, Poland
GSK Investigational Site

Poznan, 60-569, Poland
GSK Investigational Site

Szczecin, 70-111, Poland
GSK Investigational Site

Warsaw, 04-141, Poland
GSK Investigational Site

Barcelona, 08035, Spain
GSK Investigational Site

Barcelona, 08036, Spain
GSK Investigational Site

Donostia / San Sebastian, 20014, Spain
GSK Investigational Site

Madrid, 28027, Spain
GSK Investigational Site

Madrid, 28041, Spain
GSK Investigational Site

Málaga, 29010, Spain
GSK Investigational Site

Málaga, 41014, Spain
GSK Investigational Site

Murcia, 14004, Spain
GSK Investigational Site

Valencia, 46010, Spain
GSK Investigational Site

Linköping, SE-581 85, Sweden
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Lund, 222 42, Sweden
GSK Investigational Site

Stockholm, SE-171 76, Sweden
GSK Investigational Site

Uppsala, 751 85, Sweden
GSK Investigational Site

Adapazarı, 54290, Turkey (Türkiye)
GSK Investigational Site

Ankara, 06230, Turkey (Türkiye)
GSK Investigational Site

Istanbul, 34093, Turkey (Türkiye)
GSK Investigational Site

Istanbul, 34098, Turkey (Türkiye)
GSK Investigational Site

Istanbul, 34147, Turkey (Türkiye)
GSK Investigational Site

Chernihiv, 14029, Ukraine
GSK Investigational Site

Kharkiv, 61024, Ukraine
GSK Investigational Site

Brighton, BN2 5BE, United Kingdom
GSK Investigational Site

Cambridge, CB2 0QQ, United Kingdom
GSK Investigational Site

London, NW1 2PG, United Kingdom
GSK Investigational Site

London, SE1 9RT, United Kingdom
GSK Investigational Site

Truro, TR1 3LJ, United Kingdom

Conditions

Explore the condition pages connected to this study.

NEOPLASMS